Accuretic combines two types of blood pressure medication.
Accuretic does not cure high blood pressure it merely keeps it under control.
Accuretic is not prescribed for the initial treatment of high blood pressure.
Diuretics often wash too much potassium out of the body along with the water.
However, the ACE inhibitor part of Accuretic tends to keep potassium in the body, thereby canceling this unwanted effect.
In addition, some doctors are using Accuretic along with other drugs to treat congestive heart failure.
It is saved for later use, when a single blood pressure medication is not sufficient for the job.
It works by preventing a chemical in your blood called angiotensin I from converting into a more potent form (angiotensin II) that increases salt and water retention in the body and causes the blood vessels to constrict--two actions that tend to increase blood pressure.
The first, quinapril hydrochloride, is an ACE (angiotensin-converting enzyme) inhibitor.
To aid in clearing excess water from the body, Accuretic contains hydrochlorothiazide, a diuretic that promotes production of urine.
You must take Accuretic regularly for it to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Accuretic and you must continue taking it even if you are feeling well.
Accuretic side effects that you should report to your health care professional or doctor as soon as possible:
More common side effects may include:
Less common side effects may include:
- Viral infection;
- Vertigo (loss of balance);
- Upper respiratory infection;
- Stomach pain;
- Sore throat;
- Runny nose;
- Nausea and/or vomiting;
- Muscle aches;
- Chest pain;
- Back pain;
- Abdominal pain;
Rare side effects may include:
- Vague feeling of illness;
- Slow or rapid heartbeat;
- Skin blistering or peeling;
- Severe allergic reactions;
- Sensitivity to light;
- Kidney failure;
- Joint pain;
- Itchy skin;
- Irregular heartbeat;
- Inflammation of the sinuses;
- Inflammation of the pancreas;
- Increased sweating;
- Heart failure;
- Heart attack;
- Hair loss;
- Extremely high blood pressure;
- Dry mouth or throat;
- Dizziness upon standing;
- Difficult or labored breathing;
- Crushing chest pain;
- Bull's eye rash;
- Bleeding in the stomach or intestines;
- Abnormal skin sensations (such as burning or prickling);
Accuretic is contraindicated if you have any of the following conditions:
- If you are unable to urinate;
- If you are sensitive to or have ever had an allergic reaction to any of the following: accupril, thiazide diuretics such as hydrodiuril and esidrix, ace inhibitors such as capoten and vasotec, or sulfa or other sulfonamide-derived drugs such as bactrim and septra;
- If you develop any type of infection such as a sore throat or fever;
- If you develop swelling of the face, lips, tongue or throat, or of your arms and legs;
- If you have a history of allergies;
- If you have diabetes;
- If you have difficulty swallowing or breathing;
- If you have kidney disease;
- If you have liver disease;
- If you notice a yellow tinge to your skin and the whites of your eyes;
Do not take Accuretic with any of the following drugs:
- Tetracycline (achromycin v, sumycin);
- Salt substitutes containing potassium;
- Potassium-sparing diuretics such as aldactone, dyazide, and moduretic;
- Potassium supplements such as slow-k and k-dur;
- Other high blood pressure medications such as aldomet;
- Norepinephrine (levophed);
- Nonsteroidal anti-inflammatory drugs such as naprosyn;
- Narcotics such as percocet;
- Lithium (eskalith, lithobid);
- Diuretics such as hydrodiuril and lasix;
- Digoxin (lanoxin);
- Diabetes medications such as insulin or micronase;
- Corticosteroids such as prednisone or acth;
- Colestipol (colestid);
- Cholestyramine (questran);
- Barbiturates such as phenobarbital;
Accuretic is usually taken once a day.
Daily doses of up to 80 milligrams of quinapril and 50 milligrams of hydrochlorothiazide may be prescribed, but doctors aim for the smallest dose that proves effective.
Your doctor will adjust the dosage depending on how your blood pressure responds.
Symptoms of Accuretic overdose may include:
- Weakness and dizziness;
- Weak or irregular heartbeat;
- Nausea and vomiting;
- Muscle pain or cramps;
- Excessive thirst;
- Dry mouth;
- A severe drop in blood pressure;