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Amphotericin

Structure

Each vial contains Amphotericin-B 50 mg

No Prescription and Dosage

Amphotericin is prescribed for the treatment:
I.V. Infusion
Systemic mycoses important pathogens are Candida spp., Aspergillus spp., Cryptococcus neoformans and Mucor spp.: a test dose of 1 mg in 250 ml 5% dextrose infused over 2-4 hours.
If no side effects 5 mg of amphotericin B in 500 ml 5% dextrose infused over 4-6 hours followed by 5-10 mg over 6 hours.
Max in 24 hours-50 mg of amphotericin-B. Maintenance with 0.6-1 mg/kg/day if no side effects are observed.
Daily monitoring of serum creatinine level. K+ supplements may be required.

Intrathecal
Fungal meningitis severe non responding to IV course:
Administered in neurological centers-initially 0.01-0.025 mg 2-4 times
weekly. Increase gradually to 0.5-1.0 mg given 2-4 times weekly.

Contraindications

Amphotericin is contraindicated if you have any of the following conditions:
- Hypersensitivity;

Package

- Vial of 50 ml;
(c) 2017