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Asacol

No Prescription

Asacol is prescribed to treat the pain and inflammation caused by ulcerative colitis.
Asacol is prescribed to treat ulcerative colitis (a condition in which part or all of the lining of the colon [large intestine] is swollen or worn away). Asacol delayed-release tablets and controlled-release capsules may be prescribed to treat ulcerative colitis that affects any part of the colon.
Asacol is in a class of drugs called anti-inflammatory agents.
Asacol suppositories and enemas should only be prescribed to treat inflammation of the lower part of the colon.
Asacol works by stopping the body from producing a certain substance that may cause pain or inflammation.

Contraindications

Asacol is contraindicated if you have any of the following conditions:
- Kidney disease;
- Liver disease;
- Pyloric stenosis;
- An unusual or allergic reaction to Asacol, salicylates, other drugs, foods, dyes, or preservatives;
- Pregnant or trying to get pregnant;
- Breast-feeding;
- Tell your doctor and pharmacist if you are allergic to Asacol, balsalazide (Colazal) olsalazine (Dipentum) salicylate pain relievers such as aspirin, choline magnesium trisalicylate, choline salicylate (Arthropan), diflunisal (Dolobid), magnesium salicylate (Doan?s, others), and salsalate sulfasalazine (Azulfidine) or any other medications. If you will be using Asacol enemas, tell your doctor if you are allergic to sulfites (substances prescribed as food preservatives and found naturally in some foods) or any foods, dyes, or preservatives. Also tell your doctor if you are allergic to any of the ingredients in the type of Asacol you will be using. Ask your pharmacist for a list of the ingredients.
- Tell your doctor and pharmacist what script and nonscript medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: aspirin or other nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn) digoxin (Lanoxicaps, Lanoxin) or other medications for ulcerative colitis such as balsalazide (Colazal), olsalazine (Dipentum), or sulfasalazine (Azulfidine). Your doctor may need to change the doses of your medications or monitor you more carefully for side effects.
- Tell your doctor if you have or have ever had pancreatitis (swelling of the pancreas), pericarditis (swelling of the sac around the heart), or liver or kidney disease. If you will be taking the delayed-release tablets, tell your doctor if you have or have ever had pyloric stenosis (condition in which the stomach does not empty normally).If you will be using the enemas, tell your doctor if you have asthma or allergies.
- Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking Asacol, call your doctor.

Interactions

Do not take Asacol with any of the following drugs:
- Digoxin;

Side Effects

Asacol side effects that you should report to your health care professional or doctor as soon as possible:
- Allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue;
- Bloody diarrhea;
- Chest pain;
- Difficulty breathing, wheezing;
- Fever;
- Pain or difficulty passing urine;
- Unusually weak or tired;
- Yellowing of the eyes or skin;
- Headache;
- Nausea, vomiting;
- Stomach gas;
- Stomach pain or cramps;
- Headache;
- Muscle or joint pain aching tightness or stiffness;
- Back pain;
- Nausea;
- Vomiting;
- Heartburn;
- Burping;
- Constipation;
- Dry mouth;
- Sore throat;
- Cough;
- Flu-like symptoms;
- Stuffy head or runny nose;
- Ear pain;
- Anxiety;
- Sweating;
- Hemorrhoids;
- Pain in the rectum;
- Difficulty falling asleep or staying asleep;
- Acne;

Dosage

ADULTS

Asacol Suspension Enema

The usual dose is 1 rectal enema (60 ml) per day, preferably prescribed at bedtime and retained for about 8 hours. Treatment time usually lasts from 3 to 6 weeks, although improvement may be seen within 3 to 21 days.

Suppositories

The usual dose is one rectal suppository (500 mg) 2 times a day. To get the most benefit from the suppository, it should be retained for 1 to 3 hours or longer. Treatment time usually lasts from 3 to 6 weeks, although improvement may be seen within 3 to 21 days. The dosage of Canasa may be increased to 3 suppositories daily if response is unsatisfactory after 2 weeks of therapy.

Pentasa Capsules

The usual dose is 4 capsules taken 4 times a day for a total of 16 capsules daily.

Asacol Tablets

The recommended dose for the treatment of ulcerative colitis is 2 tablets 3 times a day for 6 weeks.

To prevent a relapse, the usual dosage is 4 tablets a day, taken in 2 or more smaller doses, for 6 months.

CHILDREN

Safety and effectiveness in children have not been established.

(c) 2017