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Azulfidine

No Prescription

Azulfidine, an anti-inflammatory medicine, is prescribed for the treatment of mild to moderate ulcerative colitis (a long-term, progressive bowel disease) and as an added treatment in severe ulcerative colitis (chronic inflammation and ulceration of the lining of large bowel and rectum, the main symptom of which is bloody diarrhea).
Although ulcerative colitis rarely disappears completely, the risk of recurrence can be substantially reduced by the continued use of this drug.
Azulfidine EN-tabs are prescribed for people with ulcerative colitis who cannot take the regular Azulfidine tablet because of symptoms of stomach and intestinal irritation such as nausea and vomiting when taking the first few doses of the drug, or for those in whom a reduction in dosage does not lessen the stomach or intestinal side effects.
The EN-tabs are prescribed for adults and children with rheumatoid arthritis who fail to get relief from salicylates (such as aspirin) or other nonsteroidal anti-inflammatory drugs (such as ibuprofen).
This medication is prescribed to decrease severe attacks of ulcerative colitis.

Side Effects

Azulfidine side effects that you should report to your health care professional or doctor as soon as possible:

More common side effects may include:
- Vomiting;
- Stomach distress;
- Rash;
- Nausea;
- Lack of appetite;
- Itching;
- Inflammation of the mouth;
- Hives;
- Headache;
- Fever;
- Bluish skin;
- Anemia;
- Abdominal pain;

Less common or rare side effects may include:
- Vertigo;
- Urine discoloration;
- Urinary tract infections;
- Swelling around the eye;
- Spinal cord defects;
- Skin disorders;
- Skin discoloration;
- Severe allergic reaction;
- Sensitivity to light;
- Ringing in the ears;
- Red;
- Raised rash;
- Mental depression;
- Loss of hair;
- Lack of muscle coordination;
- Kidney disorders;
- Joint pain;
- Itchy skin eruptions;
- Intestinal inflammation;
- Inability to fall or stay asleep;
- Hepatitis;
- Hearing loss;
- Hallucinations;
- Drowsiness;
- Diminished urination;
- Diarrhea;
- Convulsions;
- Bloody diarrhea;
- Blood in the urine;
- Blood disorders;

Contraindications

Azulfidine is contraindicated if you have any of the following conditions:
- If azulfidine en-tabs are eliminated un-disintegrated;
- If you are sensitive to or have ever had an allergic reaction to azulfidine, salicylates (aspirin), or other sulfa drugs;
- If you develop loss of appetite, nausea, or vomiting;
- If you have a severe allergy or bronchial asthma;
- If you have an intestinal or urinary obstruction or if you have porphyria (an inherited disorder involving the substance that gives color to the skin and iris of the eyes);
- If you have kidney or liver damage or any blood disease;

Interactions

Do not take Azulfidine with any of the following drugs:
- Methotrexate (rheumatrex);
- Folic acid (a b-complex vitamin);
- Digoxin (lanoxin);

Dosage

RHEUMATOID ARTHRITIS

Children aged 6 and older

The typical recommended daily dosage is 30 to 50 milligrams per 2.2 pounds of body weight, up to a maximum of 2 grams, taken in 2 equally divided doses. To reduce the chance of digestive side effects and other reactions, the doctor will probably start with a fraction of the typical dose and build up to it over a period of weeks.

Adults

Your doctor may have you start with a lower dose, then raise the dosage to 3 grams after 12 weeks.
The usual dose of Azulfidine EN-tabs is 2 grams a day, divided into smaller doses.

ULCERATIVE COLITIS

Children Aged 6 and Older

The usual recommended initial dose is 40 to 60 milligrams per 2.2 pounds of body weight in each 24-hour period, divided into 3 to 6 doses. For the longer term, the dose is usually reduced to 30 milligrams per 2.2 pounds of body weight in each 24-hour period, divided into 4 doses.

Adults

In some cases the initial dosage is set at 1 to 2 grams daily to lessen side effects.
The usual recommended initial dose of Azulfidine and Azulfidine EN-tabs is 3 to 4 grams daily divided into smaller doses (intervals between nighttime doses should not exceed 8 hours).
As therapy continues, the dose is usually reduced to 2 grams daily.

Overdose

Symptoms of Azulfidine overdose may include:
- Vomiting;
- Stomach upset;
- Nausea;
- Drowsiness;
- Convulsions;
- Abdominal pain;
(c) 2017