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Cardizem is a calcium-channel blocker. Cardizem is prescribed to treat chest pain caused by angina. Cardizem affects the amount of calcium found in your heart and muscle cells. This relaxes your blood vessels, which can reduce the amount of work the heart has to do.
Cardizem works by relaxing the blood vessels so the heart does not have to pump as hard.
Cardizem is prescribed to treat high blood pressure and to control chest pain (angina).
Cardizem is in a class of drugs called calcium-channel blockers.
Cardizem also increases the supply of blood and oxygen to the heart.


Cardizem is contraindicated if you have any of the following conditions:
- Heart problems, low blood pressure, irregular heartbeat;
- Liver disease;
- Previous heart attack;
- An unusual or allergic reaction to Cardizem, other drugs, foods, dyes, or preservatives;
- Pregnant or trying to get pregnant;
- Breast-feeding;
- Tell your doctor and pharmacist if you are allergic to Cardizem or any other drugs;
- Tell your doctor and pharmacist what script and nonscript medications you are taking especially heart and blood pressure medications such as beta-blockers digoxin (Lanoxin) quinidine (Quinaglute Quinidex) and diuretics (water pills) carbamazepine (Tegretol) cimetidine (Tagamet) cyclosporine (Neoral Sandimmune) fentanyl (Duragesic) medications to treat depression medications to treat glaucoma (increased pressure in the eye) theophylline and vitamins;
- Tell your doctor if you have or have ever had heart liver or kidney disease;
- Tell your doctor if you are pregnant plan to become pregnant or are breast-feeding If you become pregnant while taking Cardizem call your doctor;


Do not take Cardizem with any of the following drugs:
- Cisapride;
- Hawthorn;
- Pimozide;
- Ranolazine;
- Red yeast rice;
- Buspirone;
- Carbamazepine;
- Cimetidine;
- Cyclosporine;
- Digoxin;
- Local anesthetics or general anesthetics;
- Lovastatin;
- Drugs for anxiety or difficulty sleeping like midazolam and triazolam;
- Drugs for high blood pressure or heart problems;
- Quinidine;
- Rifampin, rifabutin, or rifapentine;

Side Effects

Cardizem side effects that you should report to your health care professional or doctor as soon as possible:
- Allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue;
- Confusion, mental depression;
- Feeling faint or lightheaded, falls;
- Pinpoint red spots on the skin;
- Redness, blistering, peeling or loosening of the skin, including inside the mouth;
- Slow, irregular heartbeat;
- Swelling of the ankles, feet;
- Unusual bleeding or bruising;
- Change in sex drive or performance;
- Constipation or diarrhea;
- Flushing of the face;
- Headache;
- Nausea, vomiting;
- Tired or weak;
- Trouble sleeping;
- Dizziness or lightheadedness;
- Flushing (feeling of warmth);
- Headache;
- Excessive tiredness;
- Slower heartbeat;
- Upset stomach;
- Loss of appetite;
- Vomiting;
- Diarrhea;
- Constipation;
- Stomach pain;
- Dry mouth;
- Difficulty falling asleep or staying asleep;
- Swelling of the face eyes lips tongue arms or legs;
- Difficulty breathing or swallowing;
- Fainting;
- Rash;
- Yellowing of the skin or eyes;
- Fever;
- Increase in frequency or severity of chest pain (angina);



Dosage levels are determined by each individual's needs.


The average daily dosage is between 180 mg and 360 mg, divided into 3 or 4 smaller doses.

Cardizem SR

The recommended starting dosage is 60 to 120 mg 2 times a day, to be increased to 240 to 360 mg a day.

Cardizem CD

This is a once-a-day form of this drug. For high blood pressure, starting doses range from 180 to 240 mg; for angina, 120 to 180 mg.

Cardizem LA

This is also a once-a-day drug. For high blood pressure, when prescribed alone, doses start at 180 to 240 mg and may be increased to as much as 540 mg once daily. For angina, the starting dose is 180 mg once daily with increases every 7 to 14 days if necessary.

Dilacor XR

This is another once-a-day drug. For high blood pressure, doses start at 180 to 240 mg and may be increased to as much as 540 mg. For angina, doses start at 120 mg and may be increased to 480 mg.


The usual starting dose for high blood pressure is 120 to 240 mg once a day. After the drug has taken effect--in about 2 weeks--the dose can range from 120 to 540 mg. For angina, once-daily doses start at 120 to 180 mg and may be increased to 540 mg if necessary.


Safety and effectiveness in children have not been established.

(c) 2017