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Casodex is prescribed in the treatment of cancer in the prostate.
Casodex 150mg is prescribed to treat locally advanced prostate cancer in people for whom surgical castration or other medical treatments are not appropriate or acceptable, provided the cancer has not spread to other parts of the body.
Casodex 150mg is prescribed to treat locally advanced prostate cancer, either by itself, or in addition to treatment with either radiotherapy or surgery to remove the prostate gland.
Casodex 50mg is only prescribed to treat advanced prostate cancer, and only in combination with either surgical castration, or a different type of anti-cancer drug known as a "gonadorelin analogue".
Casodex contains the active ingredient bicalutamide, which is a type of drug known as an anti-androgen.
Casodex is prescribed in two doses.
Casodex works by blocking the effects of male hormones such as testosterone.
Casodex works by preventing testosterone from binding to the androgen receptors on the prostate cancer cells.
It therefore starves prostate cancer cells of testosterone, which prevents them growing. Eventually the prostate tumour will shrink.
Prostate cancers are sensitive to testosterone, and their growth is increased in the presence of this hormone.
This class of drugs can cause a short-term worsening of symptoms before the improvement begins, and bicalutamide can prevent this.
This is because testosterone binds to androgen receptors on the prostate cancer cells, and causes changes within the cells that result in faster growth of the cancer.
Casodex is prescribed in the treatment of:
- Prostate cancer;
Casodex side effects that you should report to your health care professional or doctor as soon as possible:
- Weight gain;
- Weakness or loss of strength;
- Swelling of the lips, tongue or face;
- Pain in the back or pelvic area;
- Liver disorders;
- Hot flushes;
- Hair loss;
- Dry skin;
- Disturbances of the gut such as nausea, vomiting, diarrhoea or abdominal pain;
- Difficulty in breathing;
- Diarrhea or constipation;
- Decreased sex drive;
- Decreased sex drive or even impotence;
- Decrease in the number of platelets in the blood;
- Closing of the throat;
- Chest pain;
- Breast tenderness;
- Breast tenderness or swelling;
- Abnormal heart beats;
- Abnormal enlargement of breasts in men;
Casodex is contraindicated if you have any of the following conditions:
- If you have any other serious illness;
- If you have any serious condition;
- If you have liver disease;
Other Brand Names
In some countries Casodex may also be known as: