Compazine helps to control severe nausea and vomiting. Compazine is prescribed to treat schizophrenia. Compazine can help patients who experience anxiety that is not due to psychological illness.
Compazine is contraindicated if you have any of the following conditions:
- Blood disorders or disease;
- Liver disease or jaundice;
- Parkinson's disease;
- Uncontrollable movement disorder;
- An unusual or allergic reaction to Compazine, other drugs, foods, dyes, or preservatives;
- Pregnant or trying to get pregnant;
- Tell your doctor and pharmacist if you are allergic to Compazine, any tranquilizer, or any other drugs.
- Tell your doctor and pharmacist what script and nonscript medications you are taking, especially antihistamines, lithium (Eskalith, Lithobid), medications for depression and Parkinson's disease, muscle relaxants, narcotics (pain medication), sedatives, seizure medication, sleeping pills, and vitamins.
- Be sure a child younger than 16 years of age does not have symptoms of Reye's syndrome (sudden, severe, and persistent vomiting unusual behavior fever and seizures). Call your child's doctor immediately if your child experiences any of these symptoms. Do not give Compazine or aspirin to the child.
- Tell your doctor if you have or have ever had heart, liver, or kidney disease a bad reaction to insulin shock therapy glaucoma an enlarged prostate difficulty urinating asthma, emphysema, chronic bronchitis, or lung disease Parkinson's disease or seizures.
- Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking Compazine, call your doctor.
- If you are having surgery, including dental surgery, tell the doctor or dentist that you are taking Compazine.
- You should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how this drug affects you.
- Remember that alcohol can add to the drowsiness caused by this drug.
Do not take Compazine with any of the following drugs:
- Antidepressants like citalopram, escitalopram, fluoxetine, paroxetine, and sertraline;
- Tricyclic antidepressants like amitriptyline, clomipramine, imipramine, nortiptyline and others;
- Drugs for pain;
Compazine side effects that you should report to your health care professional or doctor as soon as possible:
- Blurred vision;
- Breast enlargement in men or women;
- Breast milk in women who are not breast-feeding;
- Chest pain, fast or irregular heartbeat;
- Confusion, restlessness;
- Dark yellow or brown urine;
- Difficulty breathing or swallowing;
- Dizziness or fainting spells;
- Drooling, shaking, movement difficulty (shuffling walk) or rigidity;
- Fever, chills, sore throat;
- Involuntary or uncontrollable movements of the eyes, mouth, head, arms, and legs;
- Stomach area pain;
- Unusually weak or tired;
- Unusual bleeding or bruising;
- Yellowing of skin or eyes;
- Difficulty passing urine;
- Difficulty sleeping;
- Sexual dysfunction;
- Skin rash, or itching;
- Jaw neck and back muscle spasms;
- Fine worm-like tongue movements;
- Rhythmic face mouth or jaw movements;
- Slow or difficult speech;
- Difficulty swallowing;
- Restlessness and pacing;
- Shuffling walk;
- Skin rash;
- Yellowing of the skin or eyes;
To Control Severe Nausea and Vomiting
Tablets: The usual dosage is one 5-mg or 10-mg tablet 3 or 4 times a day.
"Spansule" Capsules: The usual starting dose is one 15-mg capsule on getting out of bed or one 10-mg capsule every 12 hours.
The usual rectal dosage (suppository) is 25 mg, taken 2 times a day.
For Non-psychotic Anxiety
Tablets: The usual dose is 5 mg, taken 3 or 4 times a day.
"Spansule" capsule: The usual starting dose is one 15-mg capsule on getting up or one 10-mg capsule every 12 hours.
Treatment should not continue for longer than 12 weeks, and daily doses should not exceed 20 mg.
Relatively Mild Schizophrenia
The usual dose is 5 or 10 mg, taken 3 or 4 times daily.
Moderate to Severe Schizophrenia
Dosages usually start at 10 mg, taken 3 or 4 times a day. If needed, dosage may be gradually increased; 50 to 75 mg daily has been helpful for some people.
More Severe Schizophrenia
Dosages may range from 100 to 150 mg per day.
Children under 2 years of age or weighing less than 20 pounds should not be given Compazine, Antinaus, Stemitil, Prochlorperazine. If a child becomes restless or excited after taking Compazine, Antinaus, Stemitil, Prochlorperazine, do not give the child another dose.
For Severe Nausea and Vomiting
An oral or rectal dose of Compazine, Antinaus, Stemitil, Prochlorperazine is usually not needed for more than 1 day.
Children 20 to 29 Pounds
The usual dose is 2-1/2 mg 1 or 2 times daily. Total daily amount should not exceed 7.5 mg.
Children 30 to 39 Pounds
The usual dose is 2-1/2 mg 2 or 3 times daily. Total daily amount should not exceed 10 mg.
Children 40 to 85 Pounds
The usual dose is 2-1/2 mg 3 times daily, or 5 mg 2 times daily.
Total daily amount should not exceed 15 mg.
For Psychotic Disorders
Children 2 to 5 Years Old
The starting oral or rectal dose is 2-1/2 mg 2 or 3 times daily. Do not exceed 10 mg the first day and 20 mg thereafter.
Children 6 to 12 Years Old
The starting oral or rectal dose is 2-1/2 mg 2 or 3 times daily. Do not exceed 10 mg the first day and 25 mg thereafter.
In general, older people take lower dosages of Compazine, Antinaus, Stemitil, Prochlorperazine. Because they may develop low blood pressure while taking the drug, the doctor should monitor them closely. Older people (especially women) may be more susceptible to tardive dyskinesia--a possibly permanent condition. Tardive dyskinesia causes involuntary muscle spasms and twitches in the face and body. Consult your doctor for more information about these potential risks.