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Cytoxan |
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Anticancer
Cytoxan is an anticancer drug, works by interfering with the growth of malignant cells.
Cytoxan is prescribed for treat of:
- Retinoblastoma and carcinoma of the breast;
- Neuroblastoma (disseminated disease);
- Mycosis fungoides (advanced disease);
- Multiple myeloma;
- Malignant lymphomas;
- Leukemias;
- Adenocarcinoma of the ovary;
No Prescription
Cytoxan is prescribed in the treatment of the following types of cancer:
- Retinoblastoma (a malignant tumor of the retina);
- Ovarian cancer (adenocarcinoma);
- Neuroblastoma (a malignant tumor of the adrenal gland or sympathetic nervous system);
- Multiple myeloma (a malignant condition or cancer of the plasma cells);
- Malignant lymphomas (Hodgkin's disease or cancer of the lymph nodes);
- Leukemias (cancers affecting the white blood cells);
- Breast cancer;
- Advanced mycosis fungoides (cancer of the skin and lymph nodes);
Dosage
CHILDREN
"Minimal Change" Nephrotic Syndrome
The recommended oral dose is 2.5-3 milligrams per 2.2 pounds of body weight per day for a period of 60-90 days.
ADULTS AND CHILDREN
Malignant Diseases
The recommended oral dosage range is 1-5 mg per 2.2 pounds of body weight per day.
Overdose
Symptoms of overdose may include:
- Myelosuppression;
- Infection;
- Heart problems;
- Decreased bone marrow function;
- Cardiac toxicity;
Side Effects
Serious side effects of Cytoxan:
- Unusual bleeding or bruising;
- Typically of the bladder;
- The development of a secondary cancer;
- Temporary hair loss;
- Tarry or black stools;
- Swelling;
- Side or lower back pain;
- Pain in urinating or difficulty in urinating;
- One possible Cytoxan side effect is;
- Nausea and vomiting;
- Lymph nodes;
- Loss of appetite;
- Infection signs such as chills sore throat;
- Difficulty in breathing;
- Chest pain;
- Changes in bone marrow function should be detect in blood tests;
- Bone marrow;
- Blood in urine;
Brand Names
Other synonyms:
- Zyklophosphamid;
- Xyclomed;
- Senduxan;
- Sendoxan;
- Semdoxan;
- Rcra Waste Number U058;
- Procytox;
- Procytox;
- Neosar;
- Neosar;
- Mitoxan;
- Lyophilized Cytoxan;
- Ledoxina;
- Hidrofosmin;
- Hexadrin;
- Genuxal;
- Genoxal;
- Fosfaseron;
- Enduxan;
- Endoxane;
- Endoxan-Asta;
- Endoxanal;
- Endoxana;
- Endoxan;
- Endoxan(a);
- Endoxan R;
- Cytoxan;
- Cytoxan Lyoph;
- Cytophosphan;
- Cyklofosfamid;
- Cyclostin;
- Cyclophosphoramide;
- Cyclophosphane;
- Cyclophosphan;
- Cyclophosphamidum;
- Cyclophosphamide;
- Cyclophosphamide Sterile;
- Cyclophosphamide Monohydrate;
- Cyclophosphamid;
- Cycloblastin;
- Claphene;
- Clafen;
- Ciclokebir;
- Ciclodrax;
- Biodoxan;
- ASTA;
- Asta B 518;
- Alkyloxan;
Contraindications
Cytoxan is contraindicated in patients:
- Who have demonstrated a previous hypersensitivity to Cytoxan;
- With severely depressed bone marrow function;
Cytoxan is contraindicated if you have ever had an allergic reaction to Cytoxan
Cytoxan is contraindicated if you have ever had an allergic reaction to another anticancer drug:
- Streptozocin;
- Melphalan;
- Lomustine;
- Estramustine;
- Chlorambucil;
- Busulfan;
Cytoxan is contraindicated to anyone who is unable to produce normal blood cells because the bone marrow-where blood cells are made-is not functioning well.
Cytoxan is contraindicated for "minimal change" nephrotic syndrome or any other kidney disease.
Drug Reactions
Inform your pharmacist if you are taking any of the following medicines:
- Warfarin (Coumadin);
- Phenobarbital (Luminal Solfoton);
- Other chemotherapy medicine;
- Metolazone (Mykrox Zaroxolyn);
- Indapamide (Lozol);
- Hydrochlorothiazide (HCTZ HydroDiuril Esidrix Microzide Oretic);
- Digoxin (Lanoxin);
- Chlorthalidone (Hygroton Thalitone);
- Chlorothiazide (Diuril);
- Allopurinol (Zyloprim);
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