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Eskalith is prescribed to prevent and treat the manic episodes caused by manic-depressive illness.
Eskalith is in a class of medications called antimanic agents.
Eskalith is prescribed to treat and prevent episodes of mania (frenzied, abnormally excited mood) in people with bipolar disorder (manic depressive disorder a disease that causes episodes of depression, episodes of mania, and other abnormal moods).
Eskalith works by decreasing abnormal activity in the brain.
Eskalith is contraindicated if you have any of the following conditions:
- Dehydration (diarrhea or sweating);
- Heart or blood vessel disease;
- Kidney disease;
- Low level of salt in the blood, or on a low salt diet;
- An unusual or allergic reaction to Eskalith, other drugs, foods, dyes, or preservatives;
- Pregnant or trying to get pregnant;
- Tell your doctor and pharmacist if you are allergic to Eskalith or any other medications.
- Tell your doctor and pharmacist what script and nonscript medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: acetazolamide (Diamox) aminophylline angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), and trandolapril (Mavik)angiotensin II receptor antagonists such as candesartan (Atacand), eprosartan (Teveten), irbesartan (Avapro), losartan (Cozaar), olmesartan (Benicar), telmisartan (Micardis), and valsartan (Diovan) antacids such as sodium bicarbonate caffeine (found in certain medications to treat drowsiness and headaches) calcium channel blockers such as amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac, others), felodipine (Plendil), isradipine (DynaCirc), nicardipine (Cardene), nifedipine (Adalat, Procardia), nimodipine (Nimotop), nisoldipine (Sular), and verapamil (Calan, Covera, Isoptin, Verelan)carbamazepine (Tegretol) diuretics ('water pills') medications for mental illness such as haloperidol (Haldol) methyldopa (Aldomet) metronidazole (Flagyl) nonsteroidal anti-inflammatory medications (NSAIDs) such as celecoxib (Celebrex), indomethacin (Indocin), and piroxicam (Feldene) potassium iodide phenytoin (Dilantin) selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), and sertraline (Zoloft) and theophylline (Theolair, Theochron). Your doctor may have to change the doses of your medication or monitor you more carefully for side effects.
- Tell your doctor if you have or have ever had organic brain syndrome (any physical condition that affects the way your brain works) or thyroid, heart, or kidney disease. Also tell your doctor if you have severe diarrhea, excessive sweating, or fever. Call your doctor if you develop these symptoms during your treatment.
- Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking Eskalith, call your doctor.
- If you are having surgery, including dental surgery, tell the doctor or dentist that you are taking Eskalith.
Do not take Eskalith with any of the following drugs:
- Stimulant drugs prescribed to treat ADHD or narcolepsy;
- Calcium iodide;
- Drugs for high blood pressure;
- Drugs for mental problems and psychotic disturbances;
- NSAIDs, drugs for pain and inflammation, like ibuprofen or naproxen;
- Potassium iodide, KI;
- Sodium bicarbonate;
- Sodium chloride;
Eskalith side effects that you should report to your health care professional or doctor as soon as possible:
- Blurred vision;
- Clumsiness or loss of balance;
- Difficulty speaking or swallowing;
- Loss of appetite;
- Muscle weakness;
- Nausea, vomiting;
- Pain, coldness, or blue coloration of fingers or toes;
- Sensitivity to cold;
- Slow, fast, or irregular heartbeat (palpitations);
- Slurred speech;
- Swelling in the neck;
- Unusually weak or tired;
- Unusual weight gain;
- Increased thirst;
- Increased frequency and urgency to pass urine;
- Muscle twitches;
- Skin rash;
- Stomach bloating, full feeling;
- Trembling of the hands;
- Fine hand movements that are difficult to control;
- Loss of appetite;
- Stomach pain or bloating;
- Weight gain or loss;
- Dry mouth;
- Excessive saliva in the mouth;
- Tongue pain;
- Change in the ability to taste food;
- Swollen lips;
- Hair loss;
- Unusual discomfort in cold temperatures;
- Joint or muscle pain;
Reported Eskalith overdose symptoms are:
- Upset stomach;
- Muscle weakness;
The usual dosage is a total of 1,800 mg per day. Immediate-release forms are taken in 3 or 4 doses per day; long-acting forms are taken twice a day.
Your doctor will individualize your dosage according to the levels of the drug in your blood. Your blood levels will be checked at least twice a week when the drug is first prescribed and on a regular basis thereafter.
Dosage will vary from one individual to another, but a total of 900 mg to 1,200 mg per day is typical. Immediate-release forms are taken in 3 or 4 doses per day; long-acting forms are taken twice a day.
Blood levels in most cases should be checked every 2 months.
Safety and effectiveness of Eskalith in children under 12 years of age have not been established.
Older people often need less Eskalith and may show signs of overdose at a dosage younger people can handle well.