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Insulin transfers sugar from the bloodstream to the body's cells, where it is then prescribed for energy.
Glibenclamide is an anti-diabetic medication.
Glibenclamide is an oral antidiabetic medication.
Glibenclamide is prescribed alone or along with a drug called metformin (Glucophage).
Glibenclamide is prescribed along with a proper diet and a lot of exercises can control the high levels of sugar in the blood.
Glibenclamide is prescribed in patients who are suffering from gestational diabetes and diabetes type II.
Glibenclamide is prescribed to treat type 2 diabetes, the kind that occurs when the body either does not make enough insulin or fails to use insulin properly.
Glibenclamide stimulates the human organism to release its natural insulin.
There are two forms of diabetes: type 1 and type 2.
Type 1 diabetes results from a complete shutdown of normal insulin production and usually requires insulin injections for life, while type 2 diabetes can usually be treated by dietary changes, exercise, and/or oral antidiabetic medications such as Glibenclamide.

Glibenclamide is prescribed to prevent:
- Blindness;
- Circulation problems;
- Heart disease;
- Kidney disease;
- Sexual problems such as impotence;
- Strokes;

Side Effects

Glibenclamide side effects that you should report to your health care professional or doctor as soon as possible:
- Anemia and other blood disorders;
- Bloating;
- Blurred vision;
- Breathing problems;
- Changes in taste;
- Cold sweat;
- Coma;
- Confusion and speaking problems;
- Dizziness;
- Drowsiness;
- Fast heartbeat;
- Fatigue;
- Headache;
- Heartburn;
- Hives;
- Hunger and thirst;
- Itching and sensitivity to the sun;
- Itching;
- Joint pain;
- Liver problems;
- Muscle pain;
- Nausea and vomiting;
- Nausea;
- Nervousness;
- Pale skin;
- Rashes;
- Reddening of the skin;
- Seizures;
- Shallow breathing;
- Skin eruptions;
- Skin rash;
- Stomach problems;
- Sweating;
- Vomiting;
- Yellowing of the skin;


Glibenclamide is contraindicated if you have any of the following conditions:
- If they are suffering from any medical condition;
- If they have other medical conditions in which their insulin needs changed frequently;
- If you are suffering from diabetic ketoacidosis;
- If you have a heart condition;
- If you have adrenal and pituitary gland and weakened physical condition;
- If you have had an allergic reaction to Glibenclamide;
- If you have had an allergic reaction to similar drugs such as glucotrol or diabinese;
- If you have heart disease;
- If you have kidney and liver problems;
- If you have overactive thyroid;
- If you have underactive thyroid;


Do not take Glibenclamide with any of the following drugs:
- Airway-opening drugs such as proventil and ventolin;
- Anabolic steroids such as testosterone and danazol;
- Antacids such as mylanta;
- Aspirin;
- Beta blockers such as the blood pressure medications inderal and tenormin;
- Blood thinners such as coumadin;
- Calcium channel blockers such as the blood pressure medications cardizem and procardia;
- Certain antibiotics such as cipro;
- Chloramphenicol (chloromycetin);
- Cimetidine (tagamet);
- Clofibrate (atromid-s);
- Diuretics;
- Estrogens such as premarin;
- Estrogens;
- Fluconazole (diflucan);
- Fluoroquinolone antibiotics;
- Furosemide (lasix);
- Gemfibrozil (lopid);
- Isoniazid (nydrazid);
- Itraconazole (sporanox);
- Major tranquilizers such as stelazine and mellaril;
- Mao inhibitors such as the antidepressants nardil and parnate;
- Metformin (glucophage);
- Niacin (niacor, niaspan);
- Niacin;
- Nonsteroidal anti-inflammatory drugs such as advil, motrin, naprosyn, and voltaren;
- Oral contraceptives;
- Oral contraceptives;
- Oxidase inhibitors;
- Phenytoin (dilantin);
- Probenecid (benemid);
- Steroids such as prednisone;
- Sulfa drugs such as bactrim or septra;
- Thiazide diuretics such as the water pills diuril and hydrodiuril;
- Thyroid medications such as synthroid;



The safety and effectiveness of Glibenclamide have not been established in children.


Maintenance therapy usually ranges from 1.25 to 20 mg daily.
Usually the doctor will prescribe an initial daily dose of 2.5 to 5 mg.
In most cases, Glibenclamide is taken once a day; however, people taking more than 10 mg a day may respond better to twice-a-day dosing.
Daily doses greater than 20 mg are not recommended.


Older, malnourished or debilitated individuals, or those with impaired kidney and liver function, usually receive lower initial and maintenance doses to minimize the risk of low blood sugar (hypoglycemia).


Reported Glibenclamide overdose symptoms are:
- Blurry vision;
- Coma;
- Confusion;
- Difficulty speaking and even loss of life;
- Dizziness;
- Hunger;
- Irritability;
- Loss of consciousness;
- Pale skin;
- Seizure;
- Shaking;
- Shallow breathing;
- Sweating;

Other Brand Names

- Aglucil;
- Agobilina;
- Amecladin;
- Basstiverit;
- Benclamid;
- Benclamin;
- Bevoren;
- Calabren;
- Clamiben;
- Deroctyl;
- Diabe Pass;
- Diabemin;
- Diabetamide;
- Diabetty's;
- Diabexil;
- Diabitor;
- Dia-Eptal;
- Duraglucon N;
- Euglucan;
- Euglucon;
- Gardoton;
- Gen-Glybe;
- Gilemal;
- Glemicid;
- Glentor;
- Glibemida;
- Glibenbeta;
- Glibenclamide;
- Glibenclamon;
- Glib-ratiopharm;
- Glimel;
- Glionil;
- Gliptid;
- Glitisol;
- Glitral;
- Glucobene;
- Glukovital;
- Glybovin;
- Glymod;
- GON;
- Hemi-Daonil;
- Hemi-Doanil;
- Hexaglucon;
- Humedia;
- Libanil;
- Lisaglucon;
- Lodulce;
- Maninil;
- Mezalit;
- Mibeclag;
- Norboral;
- Origlucon;
- Pira;
- Reglusan;
- Semi-Daonil;
- Semi-Euglucon N;
- Semi-Euglucon;
- Siruc;
- Xeltic;
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