Glucotrol helps to treat type 2 diabetes. Treatment is combined with diet and exercise. Glucotrol helps your body to use insulin better.
Glucotrol is contraindicated if you have any of the following conditions:
- Diabetic ketoacidosis;
- Glucose-6-phosphate dehydrogenase deficiency;
- Heart disease;
- Kidney disease;
- Liver disease;
- Severe infection or injury;
- Thyroid disease;
- An unusual or allergic reaction to Glucotrol, sulfa drugs, other drugs, foods, dyes, or preservatives;
- Pregnant or trying to get pregnant;
- Tell your doctor and pharmacist if you are allergic to Glucotrol or any other drugs.
- Tell your doctor and pharmacist what script and nonscript medications you are taking, especially antibiotics, anticoagulants ('blood thinners') such as warfarin (Coumadin), dexamethasone (Decadron), diuretics ('water pills'), estrogens, isoniazid (INH), MAO inhibitors [phenelzine (Nardil) and tranylcypromine (Parnate)], medications for high blood pressure or heart disease, niacin, oral contraceptives, phenytoin (Dilantin), prednisone, probenecid (Benemid), and vitamins.
- Tell your doctor if you have or have ever had kidney, liver, heart, or thyroid disease or a severe infection.
- Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking Glucotrol, call your doctor.
- If you are having surgery, including dental surgery, tell the doctor or dentist that you are taking Glucotrol.
Do not take Glucotrol with any of the following drugs:
- Drugs for fungal or yeast infections;
- Alcohol containing beverages;
- Aspirin and aspirin-like drugs;
- Female hormones, like estrogens or progestins and birth control pills;
- Heart drugs;
- Male hormones or anabolic steroids;
- Drugs for weight loss;
- Drugs for allergies, asthma, cold, or cough;
- Drugs for mental problems;
- Drugs called MAO Inhibitors like Nardil, Parnate, Marplan, Eldepryl;
- NSAIDs, drugs for pain and inflammation, like ibuprofen or naproxen;
- Quinolone antibiotics like ciprofloxacin, levofloxacin, ofloxacin;
- Some herbal dietary supplements;
- Steroid drugs like prednisone or cortisone;
- Thyroid drug;
Glucotrol side effects that you should report to your health care professional or doctor as soon as possible:
- Breathing difficulties;
- Dark yellow or brown urine, or yellowing of the eyes or skin;
- Fever, chills, sore throat;
- Low blood sugar (ask your doctor or healthcare professional for a list of these symptoms);
- Severe skin rash, redness, swelling, or itching;
- Unusual bleeding or bruising;
- Nausea, vomiting;
- Stomach discomfort;
- Skin rash;
- Itching or redness;
- Exaggerated sunburn;
- Yellowing of the skin or eyes;
- Light-colored stools;
- Dark urine;
- Unusual bleeding or bruising;
- Sore throat;
- Extreme thirst;
- Frequent urination;
- Extreme hunger;
- Blurred vision;
- Dry mouth;
- Upset stomach and vomiting;
- Shortness of breath;
- Breath that smells fruity;
- Decreased consciousness;
- Dizziness or lightheadedness;
- Nervousness or irritability;
- Sudden changes in behavior or mood;
- Numbness or tingling around the mouth;
- Pale skin;
- Clumsy or jerky movements;
Dosage levels must be determined by each patient's needs.
The usual recommended starting dose is 5 mg taken before breakfast. Depending upon blood glucose response, your doctor may increase the initial dose in increments of 2.5 to 5 mg. The maximum recommended daily dose is 40 mg; total daily dosages above 15 mg are usually divided into 2 equal doses that are taken before meals.
The usual starting dose is 5 mg each day at breakfast. After 3 months, your doctor may increase the dose to 10 mg daily. The maximum recommended daily dose is 20 mg.
The safety and effectiveness of this drug in children have not been established.
Older people or those with liver disease usually start Glucotrol therapy with 2.5 mg. They can start Glucotrol XL treatment with 5 mg.