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Use of Glycomet is not recommended with insulin therapy.
Controlling high blood sugar helps to prevent heart disease, strokes, kidney disease, blindness, circulation problems, as well as sexual function problems (such as impotence).
Glycomet works by helping to restore the body's proper response to the insulin naturally produced by the body.
Glycomet is prescribed along with a diet and exercise program to control high blood sugar in diabetic patients.

Glycomet is an oral medication prescribed to control blood sugar levels in people with type 2 (non-insulin-dependent) diabetes. It contains two drugs commonly prescribed to lower blood sugar, rosiglitazone (Avandia) and metformin (Glucophage). Glycomet replaces the need to take these two drugs separately. It is also prescribed when treatment with Glucophage alone doesn't work. Glycomet is not, however, meant to take the place of weight loss or diet and exercise. You should continue to follow the regimen your doctor recommends.

Blood sugar levels are ordinarily controlled by the body's natural supply of insulin, which helps sugar move out of the bloodstream and into the cells to be prescribed for energy. People who have type 2 diabetes do not make enough insulin or do not respond normally to the insulin their bodies make, causing a buildup of unused sugar in the bloodstream. Glycomet helps remedy this problem in two ways: by decreasing your body's production of sugar and making your body more sensitive to its own insulin supply. Glycomet does not increase the body's production of insulin.


Glycomet is contraindicated if you have any of the following conditions:
- A lack of body fluids (dehydration);
- Breathing trouble or rapid breathing;
- Cold skin;
- Excessive alcohol use;
- Had surgery;
- Kidney or liver disease;
- Metabolic acidosis (eg, diabetic ketoacidosis);
- Muscle pain;
- Poor circulation conditions (eg severe congestive heart failure, recent heart attack or stroke);
- Serious infections;
- Type I diabetes (insulin-dependent diabetes);
- Unusual tiredness (fatigue) or severe drowsiness;
- Unusually slow or irregular heartbeat;
- X-ray or scanning procedures that require an injectable iodinated contrast drug;

Side Effects

Glycomet side effects that you should report to your health care professional or doctor as soon as possible:
- A metallic taste in the mouth;
- Back pain;
- Cough;
- Diarrhea;
- Dizziness;
- Fever;
- Headache;
- Itching;
- Joint pain;
- Nausea;
- Rashes;
- Stomach upset;
- Sudden weight gain;
- Swelling of the hands or feet (edema);
- Swelling;
- Trouble breathing;
- Trouble with breathing;
- Unusual tiredness or weakness;
- Weight gain;

Glycomet side effects that you should report to your health care professional or doctor as soon as possible:
- Viral Infection;
- Upset Stomach;
- Upper Respiratory Infection;
- Swelling;
- Sinus Inflammation;
- Nausea;
- Joint Pain;
- Headache;
- Fatigue;
- Diarrhea;
- Back Pain;
- Anemia;
- Accidental Injury;


Reported Glycomet overdose symptoms are:
- Slow or irregular heartbeat;
- Severe drowsiness;
- Rapid or troubled breathing;

Other Brand Names

In some countries Glycomet may also be known as:
- Rosiglit;
- Rosicon;
- Roglin;
- Gludex;
- Gliximina;
- Glimide;
- Gaudil;
- Diaben;
- Avandia;



Your doctor will start therapy at a low dose and increase it until your blood sugar levels are under control.

For patients who are inadequately controlled on metformin therapy alone

The recommended daily starting dose is 4 mg of rosiglitazone plus the dose of metformin you are already taking.

For patients who are inadequately controlled on rosiglitazone therapy alone

The recommended daily starting dose is 1,000 mg of metformin plus the dose of rosiglitazone you are already taking.

For patients on combination therapy taking separate doses of rosiglitazone and metformin

The usual starting dose of Glycomet is based on your current doses of rosiglitazone and metformin.

For patients who need to increase their current dose of Glycomet

The daily dose of Glycomet may be increased by increments of 4 mg of rosiglitazone and/or 500 mg of metformin, up to a maximum daily dose of 8 mg of rosiglitazone and 2,000 mg of metformin.


Children should not take Glycomet, since the safety and effectiveness of the drug have not been studied in this group.
(c) 2017