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Inderal is a beta-blocker. Beta-blockers reduce the workload on the heart and help it to beat more regularly.

Inderal is prescribed to control irregular heart rhythms (arrhythmias) and to relieve chest pain caused by angina, to treat high blood pressure.

Inderal may be helpful after a heart attack. Inderal is prescribed to help certain problems related to the thyroid gland and adrenal gland, relieve uncontrollable shaking (tremors), prevent migraine headaches.


Inderal is contraindicated if you have any of the following conditions:
- Circulation problems or blood vessel disease;
- Diabetes;
- History of heart attack or heart disease, vasospastic angina;
- Kidney disease;
- Liver disease;
- Lung or breathing disease, like asthma or emphysema;
- Pheochromocytoma;
- Slow heart rate;
- Thyroid disease;
- An unusual or allergic reaction to Inderal, other beta-blockers, drugs, foods, dyes, or preservatives;
- Pregnant or trying to get pregnant;
- Breast-feeding;


Do not take Inderal with any of the following drugs:
- Feverfew;
- Phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine;
- Sotalol;
- Aluminum hydroxide gel;
- Antipyrine;
- Barbiturates like phenobarbital;
- Cimetidine;
- Ciprofloxacin;
- Diazepam;
- Fluconazole;
- Haloperidol;
- Isoniazid;
- Drugs for cholesterol like cholestyramine or colestipol;
- Drugs to control heart rhythm;
- Drugs for high blood pressure;
- Drugs for HIV;
- Drugs for mental depression;
- Drugs for migraine headache like almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan;
- NSAIDs, drugs for pain and inflammation, like ibuprofen or naproxen;
- Phenytoin;
- Rifampin;
- Teniposide;
- Theophylline;
- Thyroid drugs;
- Tolbutamide;
- Warfarin;
- Zileuton;

Side Effects

Inderal side effects that you should report to your health care professional or doctor as soon as possible:
- Allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue;
- Breathing problems;
- Changes in blood sugar;
- Cold hands or feet;
- Difficulty sleeping, nightmares;
- Dry peeling skin;
- Hallucinations;
- Muscle cramps or weakness;
- Slow heart rate;
- Swelling of the legs and ankles;
- Vomiting;
- Change in sex drive or performance;
- Diarrhea;
- Dry sore eyes;
- Hair loss;
- Nausea;
- Weak or tired;



All dosages of Inderal, for any problem, must be tailored to the individual. Your doctor will determine when and how often you should take this drug. If you are over 65, the doctor will probably start with a relatively low dosage. Remember to take it exactly as directed.


The usual starting dose is 40 mg 2 times a day. This dose may be in combination with a diuretic. Dosages are gradually increased to between 120 mg and 240 mg per day for maintenance. In some cases, a dose of 640 mg per day may be needed. Depending on the individual, maximum effect of this drug may not be reached for a few days or even several weeks. Some people may do better taking this medication 3 times a day.

Angina Pectoris

The usual daily dosage is 80 mg to 320 mg, divided into 2, 3, or 4 smaller doses. When your treatment is being discontinued, your doctor will reduce the dosage gradually over a period of several weeks.

Irregular Heartbeat

The usual dose is 10 mg to 30 mg 3 or 4 times a day, before meals and at bedtime.

Heart Attack

The usual daily dosage is 180 mg to 240 mg divided into smaller doses. The usual maximum dose is 240 mg, although your doctor may increase the dose when treating heart attack with angina or high blood pressure.


The usual starting dosage is 80 mg per day divided into smaller doses. Dosages can be increased gradually to between 160 mg and 240 mg per day. If this dose does not relieve your symptoms in 4 to 6 weeks, your doctor will slowly take you off the drug.


The usual starting dose is 40 mg, 2 times per day. Symptoms will usually be relieved with a dose of 120 mg per day; however, on occasion, dosages of 240 mg to 320 mg per day may be necessary.

Hypertrophic Subaortic Stenosis

The usual dose is 20 mg to 40 mg, 3 to 4 times a day, before meals and at bedtime.

Before Adrenal Gland Surgery

The usual dose is 60 mg a day divided into smaller doses for 3 days before surgery in combination with an alpha-blocker drug.

Inderal may also be taken by people with inoperable tumors in doses of 30 mg a day, divided into smaller doses.


Inderal will be carefully individualized for use in children and is prescribed only for high blood pressure. Doses in children are calculated by body weight, and range from 2 mg to 4 mg per 2.2 pounds daily, divided into 2 equal doses. The maximum dose is 16 mg per 2.2 pounds per day.

If treatment is stopped, this drug must be gradually reduced over a 7- to 14-day period.

Inderal is also available in a sustained-release formulation, called Inderal LA, for once-a-day dosing.

(c) 2017