Indinavir is prescribed in the treatment of human immunodeficiency virus (HIV) infection. HIV causes the immune system to break down so that it can no longer fight off other infections. This leads to the fatal disease known as acquired immune deficiency syndrome (AIDS).
HIV thrives by taking over the immune system's vital CD4 cells (white blood cells) and using their inner workings to make additional copies of itself. Indinavir belongs to a class of HIV drugs called protease inhibitors, which work by interfering with an important step in the virus's reproductive cycle. Although Indinavir cannot eliminate HIV already present in the body, it can reduce the amount of virus available to infect other cells.
Indinavir can be taken alone or in combination with other HIV drugs such as Retrovir. Because Indinavir and Retrovir attack the virus in different ways, the combination is likely to be more effective than either drug alone.
Indinavir side effects that you should report to your health care professional or doctor as soon as possible:
- Sore Throat Or Upper Respiratory Tract Infection;
- Redistribution Of Body Fat;
- Pain In The Side;
- Loss Of Appetite;
- Liver Problems;
- Kidney Stones;
- Jaundice (Yellowish Skin Or Eyes Especially In Children);
- Dry Skin;
- Changes In Taste;
- Bladder Stones;
- Back Pain;
- Acid Regurgitation;
- Abdominal Pain;
The recommended dose of Indinavir is 800 mg (usually two 400-mg capsules) every 8 hours. Your doctor may lower the dose to 600 mg every 8 hours if you have mild-to-moderate liver problems due to cirrhosis. The dose will also need adjustment if you are taking Rescriptor, Mycobutin, Nizoral, Sporanox, or Videx.
Indinavir is more likely to cause kidney stones in children than in adults. If the doctor finds it necessary to prescribe Indinavir anyway, dosage is calculated according to the size of the child.