It does not completely eradicate the virus, and you may continue to develop the rare infections that attack when the immune system weakens.
It's important to remember that Kaletra does not eliminate the danger of transmitting the virus to others.
Kaletra combats the human immunodeficiency virus (HIV). HIV is the deadly virus that undermines the infection-fighting capacity of the body's immune system, eventually leading to AIDS.
Kaletra is a combination of two drugs, lopinavir and ritonavir (Norvir), both of which fall into the drug category known as protease inhibitors.
When taken along with other HIV drugs, Kaletra lowers the amount of the virus circulating in the bloodstream.
Combining Kaletra with certain other medications can cause serious, even life-threatening, reactions. Never take Kaletra with the following:
- Triazolam (halcion);
- Propafenone (rythmol);
- Pimozide (orap);
- Migraine remedies based on ergot, including cafergot, d.h.e. 45, methergine, migranal, and wigraine;
- Midazolam (versed);
- Flecainide (tambocor);
Kaletra side effects that you should report to your health care professional or doctor as soon as possible:
More common side effects may include:
- Abnormal stools;
- Abdominal pain;
Less common side effects may include:
- Mental changes;
- Lack of muscle coordination;
- Kidney stones;
- Joint disorders;
- Joint aches;
- Inflammations in the digestive tract;
- Inflamed and peeling skin;
- Increased appetite;
- Inability to control bowels;
- Hair loss;
- General feeling of illness;
- Gallbladder disorders;
- Flu-like symptoms;
- Facial swelling or paralysis;
- Eye disorders;
- Enlarged abdomen;
- Ear infection;
- Dry skin;
- Dry mouth;
- Disorders of the nervous system;
- Digestive problems;
- Difficulty swallowing;
- Difficulty breathing;
- Decreased sex drive;
- Chest pain;
- Breast growth in males;
- Bloody diarrhea;
- Blood clots;
- Benign skin growth;
- Back pain;
- Appetite changes;
- Alterations in taste sensation;
- Abnormal vision;
- Abnormal urine;
- Abnormal thinking;
- Abnormal ejaculation;
- Abnormal dreams;
Kaletra is contraindicated if you have any of the following conditions:
- If you already have diabetes;
- If you develop symptoms of this problem, such as nausea, vomiting, and abdominal pain;
- If you have a history of liver disease, including hepatitis;
- If you prove to be allergic to either lopinavir or ritonavir;
- If your blood sugar becomes difficult to control;
Do not take Kaletra with any of the following drugs:
- Warfarin (coumadin);
- St. john's wort (also called hypericum perforatum);
- Metronidazole (flagyl);
- Immunosuppressants such as neoral and prograf;
- Heart medications such as adalat, cardene, plendil, procardia;
- Drugs prescribed to treat tuberculosis, such as mycobutin, rifadin, rifater;
- Drugs prescribed to treat heart arrhythmias, such as cordarone, lidocaine, quinidex, rhythmol;
- Disulfuram (antabuse);
- Dexamethasone (decadron);
- Clarithromycin (biaxin);
- Certain hiv drugs such as videx, viramune;
- Certain cholesterol-lowering agents, including lipitor, mevacor, and zocor;
- Atovaquone (mepron);
- Antifungals such as nizoral and sporanox;
- Anticonvulsants such as dilantin, phenobarbital, tegretol;
Aged 6 Months to 12 Years
It should be taken twice a day with food and should be administered using a calibrated dosing syringe.
The dose of Kaletra for children is based on body weight.
The dose may be increased if the child is taking Viramune.
The dose may be increased to 4 capsules twice daily if Kaletra is prescribed in conjunction with Viramune.
The usual dose is 3 capsules twice daily with food.
Kaletra Oral Solution
The dose may be increased to 6.5 milliliters twice daily if Kaletra is prescribed in conjunction with Viramune.
Take 5 milliliters (1 teaspoonful) twice daily with food.
Any medication taken in excess can have serious consequences.
If a child swallows more than the recommended dose, contact your local poison control center immediately.
If you suspect an overdose, seek medical attention immediately.
Kaletra oral solution contains a high percentage of alcohol, which could be dangerous to a young child.
Little is known about Kaletra overdose.