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Lamictal

Form.

Tablets: 25 milligrams,
Tablets: 100 milligrams,
Tablets: 150 milligrams,
Tablets: 200 milligrams.

No Prescription

Lamictal is prescribed in combination with other anti-seizure drugs in the treatment of some types of seizures.
Lamictal is prescribed alone for treating partial seizures in patients 16 years and older when converting from the anti-epileptic drug valproate.
Lamictal is prescribed to control partial seizures in people with epilepsy. It is also prescribed to control a serious form of epilepsy known as Lennox-Gastaut syndrome. Lamictal is prescribed in combination with other antiepileptic medications or as a replacement for a medication such as Tegretol, Dilantin, phenobarbital, or Mysoline.

In addition, Lamictal is prescribed to help prevent the manic and/or depressive phases of bipolar disorder.

Dosage.

The initial dose of Lamictal in patients not taking valproic acid (Depakote) is 50 milligrams once daily for two weeks, followed by 100 milligrams daily given in two divided doses for two weeks. Thereafter, the usual maintenance dose is 300 to 500 milligrams daily given in two divided doses.
In patients taking valproic acid, the initial dose of Lamictal is 25 milligrams every other day for two weeks, then 25 milligrams once daily for two weeks, slowly increasing the dose (by 25 to 50 milligrams per day) every one to two weeks) until a dose of 100 to 150 milligrams daily is reached. Standard doses of Lamictal are given twice daily.

ADULTS

For Seizures

Lamictal combined with Tegretol, Dilantin, Phenobarbital, or Mysoline

One 50-mg dose per day for 2 weeks, then two 50-mg doses per day, for 2 weeks. After that, your doctor will have you take a total of 300 mg to 500 mg a day, divided into 2 doses.

Lamictal combined with Depakene or Depakote, whether taken alone or with any of the above medications

One 25-mg dose every other day for 2 weeks, then 25 mg once a day for 2 weeks. After that, the doctor will prescribe a total of 100 mg to 400 mg a day, taken in 1 or 2 doses.

Lamictal as a replacement for Tegretol, Dilantin, Phenobarbital, Mysoline, or Valproate

While you continue to take Tegretol, Dilantin, phenobarbital, or Mysoline, your doctor will add Lamictal, starting at a dose of 50 mg per day, then gradually increasing the daily dose. Once you've reached a dosage of 500 mg per day divided into 2 doses, the doctor will then begin gradually reducing the dosage of the other drug until, after 4 weeks, it has been completely eliminated. If you're switching from valproate, your doctor will have you follow a slightly different regimen.

For Bipolar Disorder

Lamictal NOT combined with Depakene, Depakote, Tegretol, Dilantin, Phenobarbital, or Mysoline

One 25-mg dose of Lamictal per day for weeks 1 and 2, then 50 mg per day for weeks 3 and 4, then 100 mg a day for week 5. After that, your doctor will have you take a total of 200 mg a day.

Lamictal combined with Depakene or Depakote

One 25-mg dose of Lamictal every other day for weeks 1 and 2, then 25 mg once a day for weeks 3 and 4, then 50 mg a day for week 5. After that, your doctor will have you take a total of 100 mg a day.

Lamictal combined with Tegretol, Dilantin, Phenobarbital, or Mysoline

One 50-mg dose of Lamictal per day for weeks 1 and 2, then 50 mg twice a day for weeks 3 and 4, then 100 mg twice a day for week 5. After that, your doctor will have you take a total of 300 to 400 mg a day, divided into 2 doses.

If you are currently taking Lamictal and the doctor tells you to stop taking any of the medications listed above--or you start or stop taking oral contraceptives or psychiatric drugs--the doctor may need to adjust your Lamictal dose accordingly.

Because there is little data on the use of Lamictal in people with liver or kidney impairment, the drug should be prescribed with caution. The doctor may have you take less than the usual dose and raise it based on your body's response.

CHILDREN 2 YEARS OF AGE AND OLDER

For Seizures

Lamictal can be added to other epilepsy drugs prescribed for children under 16 who have partial seizures or a serious form of epilepsy known as Lennox-Gastaut syndrome. Doses for children under 12 are based on the child's weight. Children 12 and older receive the adult dose. Doses are increased gradually from a low starting level to limit the risk of severe rash. Lamictal is not prescribed as a replacement drug for children under 16.

For Bipolar Disorder

Due to the lack of clinical studies, Lamictal is not recommended for treating bipolar disorder in children under 18 years old.

Side Effects.

Severe, life-threatening rashes have occurred with Lamictal. The risk in children (for whom Lamictal is not approved) is as high as 1 in 50 to 1 in 100 patients. Rash is rare in adults, but the risk is increased if the dose is increased faster than recommended or if patients also are taking valproic acid. Nearly all reported rashes have occurred within 2 to 8 weeks of starting therapy. Patients taking Lamictal should report any rash to a physician immediately.

Lamictal side effects that you should report to your health care professional or doctor as soon as possible:
- Vomiting;
- Vision Problems;
- Vertigo;
- Urinary Tract Infection;
- Uncoordinated Movements;
- Tooth Problems;
- Swelling;
- Sore Throat;
- Sleepiness;
- Sinus Infection;
- Runny Nose;
- Rash;
- Penis Disorder;
- Nervousness;
- Nausea;
- Lymph Node Problems;
- Light Sensitivity;
- Insomnia;
- Infection;
- Indigestion;
- Increased Cough;
- Hemorrhage;
- Headache;
- Fatigue;
- Facial Swelling;
- Eczema;
- Ear Problems;
- Dry Mouth;
- Double Vision;
- Dizziness;
- Convulsions;
- Constipation;
- Blurred Vision;
- Back Pain;
- Bronchitis;
- Abdominal Pain;
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