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Melphalan

Contraindications

Melphalan is contraindicated if you have any of the following conditions:
- an unusual or allergic reaction to melphalan, other chemotherapy, other medicines, foods, dyes, or preservatives;
- blood disorders;
- breast-feeding;
- infection (especially a virus infection such as chickenpox, cold sores, or herpes);
- kidney disease;
- pregnant or trying to get pregnant;
- if you are allergic to chlorambucil;
- if you are allergic to Melphalan;
- if you have any other allergies;
- if you have blood problems (bone marrow depression);
- if you have kidney problems;
- if you have previous cancer chemotherapy;
- if you have radiation treatment;

No Prescription

Melphalan belongs to a class of drugs known as alkylating agents.
Melphalan is a chemotherapy drug.
Melphalan is prescribed to treat certain types of cancer (multiple myeloma, ovarian cancer).
Melphalan is prescribed to treat multiple myeloma and ovarian cancer.
Melphalan slows the growth of cancer cells.
Melphalan works by slowing or stopping the growth of cancer cells.

Interactions

Do not take Melphalan with any of the following drugs:
- acetaminophen;
- aspirin;
- ibuprofen;
- ketoprofen;
- medicines to increase blood counts like filgrastim, pegfilgrastim, sargramostim;
- nalidixic acid;
- naproxen;
- vaccines;
- cimetidine;
- cyclosporine;
- nalidixic acid;

Side Effects

Melphalan side effects that you should report to your health care professional or doctor as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue;
- breathing problems;
- cough that does not go away;
- dark urine;
- diarrhea;
- feeling faint or lightheaded, falls;
- hair loss;
- low blood counts - this medicine may decrease the number of white blood cells, red blood cells and platelets. you may be at increased risk for infections and bleeding;
- missed menstrual periods;
- mouth sores;
- nausea;
- nausea, vomiting;
- signs of decreased platelets or bleeding - bruising, pinpoint red spots on the skin, black, tarry stools, blood in the urine;
- signs of decreased red blood cells - unusually weak or tired, fainting spells, lightheadedness;
- signs of infection - fever or chills, cough, sore throat, pain or difficulty passing urine;
- unusual bleeding or bruising;
- weight loss;
- yellowing of the eyes or skin;
- bloody/black/tarry stools;
- chest pain;
- coughing up blood;
- dark urine;
- decreased or missed menstrual periods;
- decreased sexual function;
- diarrhea;
- easy bruising/bleeding;
- itching/swelling (especially of the face/tongue/throat);
- lip/mouth sores;
- loss of appetite;
- lower back or side pain;
- nausea;
- pain/redness/swelling of the arms/legs;
- painful/difficult breathing;
- painful/difficult urination;
- persistent cough;
- pinkish urine;
- rash;
- severe dizziness;
- stomach/abdominal pain;
- trouble breathing;
- unusual lumps/masses under the skin;
- unusual tiredness;
- unusual weight loss;
- vomit that looks like coffee grounds;
- vomiting;
- yellowing eyes/skin;
(c) 2017