Tablets: 10 milligrams,
Tablets: 20 milligrams,
Tablets: 40 milligrams;
Extended release tablets: 10 milligrams,
Extended release tablets: 20 milligrams,
Extended release tablets: 40 milligrams,
Extended release tablets: 60 milligrams.
High LDL cholesterol is usually first treated with exercise, weight loss in obese individuals, and a diet low in cholesterol and saturated fats. When these measures fail, cholesterol-lowering medications such as Lovastatin can be added.
The National Cholesterol Education Program (NCEP) has published treatment guidelines for use of these medications. These treatment
guidelines take into account the level of LDL cholesterol as well as the
presence of other risk factors such as diabetes, hypertension, cigarette smoking,
low HDL cholesterol level, and family history of early coronary heart
disease. The effectiveness of the medication in lowering cholesterol is dose-
related. Blood cholesterol determinations are performed in regular
intervals during treatment so that dosage adjustments can be made. A reduction
in LDL cholesterol level can be seen two weeks after starting therapy.
Mevacor is used, along with diet, to lower cholesterol levels in people with primary hypercholesterolemia (too much cholesterol in the bloodstream). High cholesterol levels foster the buildup of artery-clogging plaque, which can be especially dangerous when it collects in the vessels serving the muscles of the heart. Mevacor is prescribed to prevent this problem--called coronary heart disease--or to slow its advance if the arteries are already clogging up.
May be taken on an empty or full stomach. The medication seems to be most effective when given with the evening meal.
The recommended starting dose is 20 mg once a day, taken with the evening meal. Your doctor may start you at 10 mg a day if you need only a small reduction in cholesterol. The maximum recommended dose is 80 mg per day, taken as a single dose or divided into smaller doses, as determined by your doctor. Adjustments to any dose, as determined by your doctor, should be made at intervals of 4 weeks or more.
If you are taking cyclosporine, Lopid, Atromid-S, Tricor, or nicotinic acid in combination with Mevacor, your dose of Mevacor should not exceed 20 mg per day. If you are taking amiodarone (Cordarone) or verapamil (Calan), your dose of Mevacor should not exceed 40 mg a day.
Cholesterol levels should be monitored periodically by your doctor, who may decide to reduce the dose if your cholesterol level falls below the targeted range.
If you have reduced kidney function, your doctor will be cautious about increasing your dosage.
CHILDREN 10 TO 17 YEARS OLD
The recommended dosage is 10 to 40 mg per day, taken with meals. Adjustments to any dose, as determined by the doctor, should be made at intervals of 4 weeks or more. Girls must have been menstruating for at least 1 year before starting therapy with Mevacor.
The safety and effectiveness of Mevacor in children under 10 years old or in doses greater than 40 mg a day have not been studied.
Side effects are rare.
Minor side effects include:
Major side effects include:
- Yellowing of the skin or eyes;
- Muscle pain or cramps;
- Blurred vision;
- Abdominal pain or cramps;
Mevacor side effects that you should report to your health care professional or doctor as soon as possible:
- Muscle Weakness With Rash;
- Muscle Pain;
- Muscle Cramps;
- Blurred Vision;
- Altered Sense Of Taste;
- Abdominal Pain/Cramps;