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Orudis is a non-steroidal anti-inflammatory drug, with antipyretic and analgesic properties, based on the action of its main active ingredient, ketoprofen.
Its anti-inflammatory, antipyretic and analgesic properties have been clearly demonstrated by both animal and in vitro testing, due to its inhibitory action on prostaglandin and leukotriene synthesis, its antibradykinin and lysosomal membrane-stabilizing activity.
Ketoprofen is included in a class of medication called NSAIDs (non-steroidal anti-inflammatory drugs), and it has an inhibitory action on the body's production of a substance causing pain, fever and inflammation.
Orudis is prescribed to relieve pain, including menstrual pain, minor aches and pain from headaches, toothaches, the common cold, muscle and backaches, and to reduce fever.
Orudis is prescribed to relieve pain, tenderness, swelling and stiffness in the joints caused by rheumatoid arthritis and Osteoarthritis.

Orudis, a nonsteroidal anti-inflammatory drug, is prescribed to relieve the inflammation, swelling, stiffness, and joint pain associated with rheumatoid arthritis and osteoarthritis (the most common form of arthritis). It is also prescribed to relieve mild to moderate pain, as well as menstrual pain.

Oruvail, an extended-release form of the drug, is prescribed to treat the signs and symptoms of rheumatoid arthritis and osteoarthritis over the long term, not severe attacks that come on suddenly.

Actron and Orudis KT are over-the-counter forms of the drug. They are prescribed to relieve minor aches and pains associated with the common cold, headache, toothache, muscle aches, backache, minor arthritis, and menstrual cramps. They are also prescribed to reduce fever.

Side Effects

Orudis side effects that you should report to your health care professional or doctor as soon as possible:
- Back pain;
- Blisters;
- Changes in vision;
- Cloudy, discolored or bloody urine;
- Constipation;
- Diarrhea;
- Difficult or painful urination;
- Difficulty breathing or swallowing;
- Difficulty falling or staying asleep;
- Dizziness;
- Drowsiness;
- Excessive tiredness;
- Fast heartbeat;
- Fever;
- Flu-like symptoms;
- Headaches;
- Hives;
- Hoarseness;
- Itching;
- Loss of appetite;
- Loss of energy;
- Nervousness;
- Pain in the upper right part of the stomach;
- Pale skin;
- Rapid and continuous gain in weight;
- Rashes;
- Ringing in the ears;
- Sores in the mouth;
- Swelling of various body parts;
- Unusual bleeding or bruising;
- Upset stomach;
- Yellowing of the skin or eyes;

Orudis side effects that you should report to your health care professional or doctor as soon as possible:
- Nervousness;
- Nausea;
- Indigestion;
- Inability To Sleep;
- Headache;
- Gas;
- Fluid Retention;
- Dreams;
- Diarrhea;
- Constipation;
- Changes In Kidney Function;
- Abdominal Pain;


Reported Orudis overdose symptoms are:
- Coma;
- Drowsiness;
- Lack of energy;
- Seizures;
- Shallow breathing;
- Stomach pain;
- Upset stomach;
- Vomiting;

Other Brand Names

In some countries Orudis may also be known as:
- Apo-Keto;
- Artrinid;
- Bi-Profenid;
- Bi-Rofenid;
- Bonil;
- Ceprofen;
- Cirus;
- Desketo;
- Dexalgin 25;
- Dexoket;
- Dolo-Ketazon;
- Dolomax;
- Effekton mit Ketoprofen;
- Enantyum;
- Fastum;
- Flogofin;
- Helenil;
- Ketartrium;
- Ketesse;
- Ketop;
- Ketoselect;
- Keydol;
- Lasonil CM;
- Lindilan;
- Lolita;
- Mohrus;
- Myproflam;
- Nosatel;
- Novo-Keto;
- Oki;
- Orofeno;
- Orudis;
- Oruvail;
- Phardol Schmerz;
- Profenid;
- Profinject;
- Prontoket;
- Pyrsal;
- Quiralam;
- Quirgel;
- Relatene;
- Rhodis;
- Rhovail;
- Rilies;
- Rofenid;
- Rofepain;
- Salicrem K;
- Siduro;
- Spondylon;
- Stadium;
- Talflex;
- Tiloket;
- Togal Mobil-Gel mit ketoprofen;
- Zon;



Rheumatoid Arthritis and Osteoarthritis

The starting dose of Orudis is 75 mg 3 times a day or 50 mg 4 times a day; for Oruvail, 200 mg taken once a day. The most you should take in a day is 300 mg of Orudis or 200 mg of Oruvail. Some side effects, such as headache or upset stomach, increase in severity as the dose gets higher.

Mild to Moderate Pain and Menstrual Pain

The usual dose of Orudis is 25 to 50 mg every 6 to 8 hours as needed.

Smaller people, older people, and those with kidney or liver disease need smaller doses of Orudis. Doses above 75 mg have no additional effect.

The usual dose of Actron or Orudis KT is 1 tablet or caplet (12.5 mg) every 4 to 6 hours. If you get no relief in 1 hour, you may take another tablet or caplet. Do not take more than 2 tablets or caplets in a 4 to 6-hour period. Do not take more than 6 tablets or caplets each 24 hours.


Not for use in children under 16 years of age, unless recommended by a doctor.


Dosage may be lower.
(c) 2017