Tablets: 10 milligrams,
Tablets: 20 milligrams,
Tablets: 40 milligrams.
Prilosec is prescribed for treating:
- Zollinger-Ellison Syndrome;
- Gastroesophageal reflux disease (GERD);
- Acid-induced inflammation and ulcers of the stomach and duodenum;
It also is prescribed in combination with antibiotics for eradicating H. pylori infection of the stomach.
Prilosec is prescribed for the short-term treatment (4 to 8 weeks) of the following:
- Duodenal Ulcer (Near The Exit From The Stomach);
- Erosive Esophagitis (Inflammation Of The Esophagus);
- Heartburn And Other Symptoms Of Gastroesophageal Reflux Disease (Also Known As Gerd Which Occurs When Stomach Acid Backs Up Into The Tube Connecting The Throat To The Stomach).;
- Stomach Ulcer;
It is also prescribed to maintain healing of erosive esophagitis and for the long-term treatment of conditions in which too much stomach acid is secreted, including Zollinger-Ellison syndrome, multiple endocrine adenomas (benign tumors), and systemic mastocytosis (cancerous cells).
Combined with the antibiotic clarithromycin (Biaxin) (and sometimes with the antibiotic amoxicillin as well), Prilosec is also prescribed to cure patients whose ulcers are caused by infection with the germ H. pylori.
In addition, Prilosec is available as an over-the-counter (OTC) product. However, Prilosec OTC is approved only for frequent heartburn (occurs two or more days a week). The script version is still needed for treatment of ulcers, esophagitis, GERD, and other conditions that require monitoring by a doctor.
For ulcers, GERD and eradication of H. pylori the recommended dose for adults is
20-40 milligrams daily.
Ulcer healing usually occurs within 4-8 weeks. H. pylori infections are
treated for 10-28 days. Prilosec OTC has been approved for more severe heartburn for
up to two weeks.
For the management of Zollinger-Ellison Syndrome the starting dose for adults is 60 milligrams daily, and the dose is adjusted based on either the response of symptoms or the actual measurement of acid production. Doses greater than 80 milligrams should be divided. Doses up to 120 milligrams three times a day have been prescribed in the treatment of Zollinger-Ellison Syndrome.
For maximal efficacy, Prilosec tablets should be taken before meals, swallowed whole and should not be crushed, chewed or opened.
Short-term Treatment of Active Duodenal Ulcer
The usual dose is 20 mg once a day. Most people heal within 4 weeks, although some require an additional 4 weeks of Prilosec therapy.
Treatment of Duodenal Ulcers Caused by H. Pylori
In combination therapy with Biaxin alone, the usual dosage is 40 mg of Prilosec once daily and 500 mg of Biaxin 3 times a day for 14 days, followed by 20 mg of Prilosec once daily for an additional 14 days.
If amoxicillin is included in the treatment, the recommended dosage is 20 mg of Prilosec, 500 mg of Biaxin, and 1,000 mg of amoxicillin twice a day for 10 days, followed by 20 mg of Prilosec once daily for an additional 18 days.
The usual dose is 40 mg once a day for 4 to 8 weeks.
Gastroesophageal Reflux Disease (GERD)
The usual dose for people with symptoms of GERD is 20 mg daily for up to 4 weeks. For erosive esophagitis accompanied by GERD symptoms, the usual dose is 20 mg a day for 4 to 8 weeks.
The dose may be continued to maintain healing.
Pathological Hypersecretory Conditions
The usual starting dose is 60 mg once a day. If you take more than 80 mg a day, your doctor will divide the total into smaller doses. The dosing will be based on your needs.
CHILDREN 2 TO 16 YEARS OLD
Gastroesophageal Reflux Disease (GERD) and Acid-Related Disorders
For children weighing less than 44 pounds, the usual dose is 10 mg a day. For those weighing 44 pounds or more, the usual dose is 20 mg a day. For children with erosive esophagitis, your doctor will determine the correct dose based on the child's weight.
The safety and effectiveness of Prilosec have not been studied in children under 2 years old.
Prilosec like other PPIs is well-tolerated.
The most common side effects are:
- Abnormal heartbeat;
- Leg cramps;
- Muscle pain;
- Water retention;
Each dose of Prilosec powder for oral suspension contains 460 milligrams of sodium, and this should be taken into consideration in patients who need a sodium restricted diet.
Prilosec side effects that you should report to your health care professional or doctor as soon as possible:
- Tongue Discoloration;
- Taste Alteration;
- Sore Throat;
- Nasal Inflammation;
- Flu Symptoms;
- Abdominal Pain;