Capsule: 200 milligrams.
Rebetol is prescribed in combination with interferon to treat patients with chronic hepatitis C who have not been treated with interferon previously
or who have had a return of hepatitis C following successful treatment with interferon.
In combination with the interferon drugs Intron A or PEG-Intron, Rebetol is prescribed to treat chronic hepatitis C. Rebetol is always prescribed with one of the other drugs. By itself, it is ineffective against hepatitis C.
Rebetol dosing is individualized based upon a patient's weight and previous use of interferon.
Rebetol may be taken with or without food. When taken orally, it should be taken consistently. For example, it should be taken at the same time or times each day and with or without food each time.
Your doctor will tailor your dosage to fit your needs. Your dosage will be lowered if you develop anemia while taking Rebetol.
TREATMENT WITH Rebetol AND INTRON A
The dosage depends on your body weight. The usual dose for individuals weighing 165 pounds or less is 400 mg in the morning and 600 mg in the evening. The usual daily dose for individuals weighing over 165 pounds is 1,200 mg divided into 2 doses.
The recommended duration of treatment for people who have not taken an interferon drug previously is 24 to 48 weeks. If you've taken interferon in the past and have had a relapse, the recommended duration of treatment is 24 weeks.
For Children 3 Years of Age and Older
Children who weigh 134 pounds or more will usually take the adult dose listed above. For children who weigh less than 134 pounds, the doctor will adjust the dose accordingly based on the child's weight.
TREATMENT WITH Rebetol AND PEG-INTRON
For Adults 18 Years of Age and Older
The usual dose is 800 mg divided into 2 doses.
The most common side effect seen with the combination of Rebetol
and interferon is a flu-like syndrome consisting of body aches and pains, fever, chills, headache and malaise.
The most serious side effect seen with Rebetol is anemia. Careful consideration
is advised if Rebetol is prescribed in patients with heart or circulation problems since the anemia may aggravate these conditions.
Rebetol should be avoided among patients who have severe kidney disease and have lost most of their kidneys' function.
Therapy with Rebetol and interferon may aggravate psychiatric conditions
or may trigger a psychiatric condition such as:
- Aggressive behavior;
- Violent behavior;
Patients should be closely monitored for the development of these psychiatric conditions.
Therapy with Rebetol and interferon has caused abnormalities of the
thyroid gland. If these abnormalities persist and cannot be controlled by
medication, it may be necessary to discontinue therapy.
Other possible side effects that may occur during therapy with Rebetol and interferon are:
- Alterations in taste perception;
- Difficulty breathing;
Rebetol side effects that you should report to your health care professional or doctor as soon as possible:
- Weight Loss;
- Shortness Of Breath;
- Joint Or Muscle Pain;
- Hair Loss;
- Blood Disorder;