Capsules: 100 milligrams;
Syrup: 50 milligrams/5 milliliters;
Injections 10 milligrams/ milliliters.
Retrovir is prescribed for the treatment of HIV and the prevention of HIV transmission from an infected mother to her fetus.
Retrovir is prescribed for adults infected with human immunodeficiency virus (HIV). HIV causes the immune system to break down so that it can no longer respond effectively to infection, leading to the fatal disease known as acquired immune deficiency syndrome (AIDS). Retrovir slows down the progress of HIV. Combining Retrovir with other drugs such as Epivir and Crixivan can help slow the progression.
Retrovir is also prescribed for HIV-infected children over 3 months of age who have symptoms of HIV or who have no symptoms but, through testing, have shown evidence of impaired immunity.
Retrovir taken during pregnancy often prevents transmission of HIV from mother to child.
Signs and symptoms of HIV disease are significant weight loss, fever, diarrhea, infections, and problems with the nervous system.
For the treatment of HIV infection the recommended oral dose for adults is 100 milligrams every 4 hours. The intravenous dose is 1 to 2 milligrams/kg every 4 hours.
For children 3 months to 12 years old, the oral starting dose is 180 milligrams/m2 every 6 hours not to exceed 200 milligrams every 6 hours.
Infants should be given 2 milligrams/kg orally every 6 hours within 12 hours of birth and for 6 weeks or 1.5 milligrams/kg intravenously every 6 hours.
To prevent HIV transmission from mother to fetus, the dose is 100 milligrams five
times daily or 200 milligrams three times daily. Treatment should be initiated
between the14th and 34th weeks of pregnancy and continued until the time of
labor. During labor and delivery, 2 milligrams/kg should be administered intravenously over 1 hr followed by 1 milligrams/kg/hr until the umbilical cord is clamped.
All dosages of Retrovir must be very closely monitored by your physician. The following dosages are general; your physician will tailor the dose to your specific condition.
Tablets, Capsules, and Syrup
The usual dose of Retrovir, in combination with other HIV drugs, is 600 mg a day, divided into smaller doses.
If you are pregnant, the usual dosage is 100 mg in capsules, tablets, or syrup 5 times a day, beginning at 14 weeks of pregnancy, until you go into labor. You will then be given the drug intravenously until the baby is born. The baby will get Retrovir every 6 hours until it is 6 weeks old.
The usual starting dose for children 6 weeks to 12 years of age is determined by body size. While the dose should not exceed 200 mg every 8 hours, it must still be individually determined. The drug is given along with other HIV medications.
The most severe side effects are:
- Muscle pain (myopathy) enlarged liver (hepatomegaly);
- Metabolic disturbance (lactic acidosis);
- A decrease in blood cells;
Other side effects are:
- Weight loss;
Retrovir side effects that you should report to your health care professional or doctor as soon as possible:
- Swollen Lymph Nodes;
- Nasal Discharge Or Congestion;
- Mouth Sores;
- Loss Of Appetite;
- General Feeling Of Illness;
- Enlarged Spleen;
- Enlarged Liver;
- Ear Pain;
- Discharge Or Swelling;
- Difficult Or Labored Breathing;