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Tibolone

Structure

Each uncoated tablet contains Tibolone 2.5 mg

No Prescription

Complaints resulting from the natural or artificial menopause.
Vasomotar symptoms in oestrogen deficiency (natural or surgical menopause) prophylaxis, osteoporosis.

Dosage

The dosage is 2.5 per day.
The tablet should be swallowed with some water or other drink, preferably at the same time of day.
Improvement of symptoms generally occurs within a few weeks, but optimal results are obtained when therapy is continued for at least 3 months.
At the recommended dosage, tibolone may be prescribed uninterrupted for longer periods.

Starting Tibolone:
Women experiencing a natural menopause should commence treatment with tibolone 12 months after their last natural bleed.
If tibolone is taken sooner than this, irregular menstrual bleeding may occur.
In the case of artifical menopause, treatment with tibolone may commence immediately switching from conventional hormone replacement therapy (HRT)

In women with a uterus who change from an estrogen - only preparation, a withdrawal bleed should be induced before starting tibolone.
If changing from sequential HRT preparation treatment with tibolone should start after the progestagen phase has been completed.
If changing from a continuous - combined HRT preparation, treatment can start at any time.
If abnormal vaginal bleeding is the reason for switching from conventional HRT, it is advised to investigate the cause of bleeding before starting tibolone.

Missed tablets:
A missed dose should be taken as soon as remembered, unless it is more that 12 hours overdue.
In the latter case, the missed dose should be skipped and the next dose should be taken at the normal time.

Children:
Not applicable

The dosage is 2.5 per day. The tablet should be swallowed with some water or other drink, preferably at the same time of day.
Improvement of symptoms generally occurs within a few weeks, but optimal results are obtained when therapy is continued for at least 3 months.
At the recommended dosage, tibolone may be prescribed uninterrupted for longer periods.

Starting Tibolone
Women experiencing a natural menopause should commence treatment with tibolone 12 months after their last natural bleed.
If tibolone is taken sooner than this, irregular menstrual bleeding may occur.

In the case of artificial menopause, treatment with tibolone may commence immediately switching from conventional hormone replacement therapy (HRT)

In women with a uterus who change from an estrogen only preparation, a withdrawal bleed should be induced before starting tibolone.
If changing from sequential HRT preparation treatment with tibolone should start after the progestogen phase has been completed.
If changing from a continuous combined HRT preparation, treatment can start at any time.
If abnormal vaginal bleeding is the reason for switching from conventional HRT, it is advised to investigate the cause of bleeding before starting tibolone.

Missed tablets
A missed dose should be taken as soon as remembered, unless it is more than 12 hours overdue.
In the latter case, the missed dose should be skipped and the next dose should be taken at the normal time.

Children
Not applicable.

Contraindications

Tibolone is contraindicated if you have any of the following conditions:
- Cardiovascular or cerebrovascular disorders e.g. thrombophlebitis, thrombo-embolic processes or a history of these conditions;
- Known or suspected hormone - dependent tumours;
- Pregnancy;
- Severe liver disorders;
- Undiagnosed vaginal bleeding;

Package

- Blister pack of 14 tablets;
(c) 2017