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Tofranil

Form.

Tablets: 10 milligrams,
Tablets: 25 milligrams,
Tablets: 50 milligrams;
Sustained-release capsules: 75 milligrams,
Sustained-release capsules: 100 milligrams,
Sustained-release capsules: 125 milligrams,
Sustained-release capsules: 150 milligrams.

No Prescription

Tofranil is prescribed to elevate the mood of patients with depression. Tofranil also causes sedation.
Tofranil is prescribed in depressed patients with insomnia, restlessness, and nervousness.
Tofranil is prescribed to treat depression. It is a member of the family of drugs called tricyclic antidepressants.

Tofranil is also prescribed on a short-term basis, along with behavioral therapies, to treat bed-wetting in children aged 6 and older. Its effectiveness may decrease with longer use.

Some doctors also prescribe Tofranil to treat bulimia, attention deficit disorder in children, obsessive-compulsive disorder, and panic disorder.

Tofranil-PM, which is usually taken once daily at bedtime, is approved to treat major depression.

Dosage.

The dose of Tofranil is tailored to the patient's needs. Sometimes, physicians will start with low doses, such as 25 milligrams, three times a day, to reduce the risk of excessive sedation; doses then will be increased slowly. Other physicians prefer to give Tofranil once daily, in which case it is generally given at bedtime to take advantage of its sedating properties. Elderly persons and patients with advanced liver disease may need lower doses since they may eliminate Tofranil less well from the body. Mood elevation occurs only in depressed individuals and not in individuals without depression. It may take 2-3 weeks of therapy before effects are seen.

For the treatment of enuresis, children 6 years or older usually are started on 10-25 milligrams, at bedtime. If this dose is not effective after 1 week, the dose may be increased by 25 milligrams/day.

For the treatment of attention-deficit hyperactivity disorder (ADHD), children ages 6-12 years old usually are started on 10-30 milligrams/day.

ADULTS

The usual starting dose is 75 mg a day. The doctor may increase this to 150 mg a day. The maximum daily dose is 200 mg. People who need to take 75 mg or more a day may use Tofranil-PM capsules instead of the regular tablets.

CHILDREN

Tofranil is not to be prescribed in children to treat any condition but bedwetting, and its use will be limited to short-term therapy. Safety and effectiveness in children under the age of 6 have not been established. Tofranil-PM should not be prescribed in children for any reason.

Total daily dosages for children should not exceed 2.5 mg for each 2.2 pounds of the child's weight.

Doses usually begin at 25 mg per day. This amount should be taken an hour before bedtime. If needed, this dose may be increased after 1 week to 50 mg (ages 6 through 11) or 75 mg (ages 12 and up), taken in one dose at bedtime or divided into 2 doses, 1 taken at mid-afternoon and 1 at bedtime.

OLDER ADULTS AND ADOLESCENTS

People in these two age groups should start with 25 to 50 mg per day of Tofranil tablets, since Tofranil-PM capsules are not available in these dosage strengths. The dose may be increased as necessary, but effective dosages usually do not exceed 100 mg a day.

Side Effects.

The most commonly encountered side effects associated with Tofranil include:
- Blurred vision;
- Dry mouth constipation;
- Fast heart rate;
- Hepatitis;
- Hives;
- Low blood pressure when standing;
- Rash;
- Seizures;
- Urinary difficulty urinating;
- Weight gain or loss;

Tofranil side effects that you should report to your health care professional or doctor as soon as possible:
- Vomiting;
- Tremors;
- Tiredness;
- Stomach And Intestinal Problems;
- Sleep Disorders;
- Numbness;
- Nausea;
- Low Blood Pressure Upon Standing;
- Hives;
- High Blood Pressure;
- Hallucinations;
- Fainting;
- Emotional Instability;
- Dry Mouth;
- Diarrhea;
- Convulsions;
- Constipation;
- Confusion;
- Collapse;
- Breast Milk Production;
- Breast Enlargement In Females;
- Nervousness;
- Breast Development In Males;
- Anxiety;
(c) 2017