By interfering with this protein, Trastuzumab can stop cancer cell growth.
This protein is found in roughly 25 to 30 percent of breast cancers.
Trastuzumab is a monoclonal antibody.
Trastuzumab is called a monoclonal antibody.
Trastuzumab is prescribed alone or with other medications to treat certain types of breast cancer (tumors that produce more than the normal amount of a certain substance called HER2 protein).
Trastuzumab is prescribed with other cancer treatments.
Trastuzumab may also destroy the cancer cells or signal the body (immune system) to destroy the cancer cells.
Trastuzumab targets a protein called HER2.
Trastuzumab works by attaching to the HER2 cancer cells and blocking them from dividing and growing.
Trastuzumab side effects that you should report to your health care professional or doctor as soon as possible:
- Bone pain;
- breathing difficulties;
- chest pain or palpitations;
- dizziness or fainting;
- Fast/pounding heartbeat;
- fever or chills, sore throat;
- Increased coughing;
- Itching/swelling (especially of the face/tongue/throat);
- Loss of appetite;
- loss of appetite;
- Mental/mood changes;
- muscle aches;
- Muscle/joint/back pain;
- Redness/irritation at injection (IV) site;
- Severe dizziness;
- Severe headache;
- skin rash, itching or hives;
- Slurred speech;
- Stomach/abdominal pain;
- Swelling of the hands/ankles/feet;
- swelling of the legs or ankles;
- Tingling/numbness (in the hands / feet / leg);
- Trouble breathing;
- Trouble sleeping;
- Unusual tiredness;
- unusually weak or tired;
- Vision changes;
- Weakness on one side of the body;
Trastuzumab is contraindicated if you have any of the following conditions:
- an unusual or allergic reaction to trastuzumab, benzyl alcohol, or other medications, foods, dyes, or preservatives;
- heart disease;
- heart failure;
- infection (especially a virus infection such as chickenpox, cold sores, or herpes);
- lung or breathing disease, like asthma;
- pregnant or trying to get pregnant;
- recent or ongoing radiation therapy;
- if you are allergic to benzyl alcohol;
- if you are allergic to other mouse protein medications;
- if you are allergic to trastuzumab;
- if you have any other allergies;
- if you have current infection;
- if you have heart disease;
- if you have high blood pressure;
- if you have lung problems;
- if you have previous cancer treatments (including radiation therapy to the chest);
- if you have previous severe reaction to monoclonal antibody treatment;
- if you have virus infection with returning symptoms (herpes, shingles);
Do not take Trastuzumab with any of the following drugs:
- Corticosteroids such as prednisone;
- Current or previous use of other anti-cancer drugs;
- Drugs for high blood pressure;
- Drugs that affect the immune system;
- Measles vaccine;
- Polio vaccine taken by mouth;
- Recent or planned immunizations;