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Trileptal

No Prescription

Trileptal is prescribed to treat people with epilepsy. Trileptal helps prevent partial seizures.
Trileptal is in a class of drugs called anticonvulsants.
Trileptal is prescribed alone or in combination with other drugs to treat certain types of seizures in people who have epilepsy.
Trileptal works by decreasing abnormal excitement in the brain.

Contraindications

Trileptal is contraindicated if you have any of the following conditions:
- Kidney disease;
- Liver disease;
- Suicidal thoughts, plans, or attempt a previous suicide attempt by you or a family member;
- Any unusual or allergic reaction to Trileptal, carbamazepine, other drugs, foods, dyes, or preservatives;
- Pregnant or trying to get pregnant;
- Breast-feeding;
- Tell your doctor and pharmacist if you are allergic to Trileptal, carbamazepine (Carbatrol, Epitol, Equetro, Tegretol), any other medications, or any of the inactive ingredients in Trileptal tablets or suspension. Ask your pharmacist for a list of the inactive ingredients in Trileptal tablets or suspension.
- Tell your doctor and pharmacist what script and nonscript medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: amiodarone (Cordarone) amitriptyline (Elavil) calcium channel blockers such as amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac), felodipine (Plendil), isradipine (DynaCirc), nicardipine (Cardene), nifedipine (Procardia), nimodipine (Nimotop), nisoldipine (Sular), and verapamil (Calan, Covera, Isoptin, Verelan) chlorpromazine (Thorazine)clomipramine (Anafranil)cyclophosphamide (Cytoxan, Neosar) desmopressin (DDAVP, Minirin, Stimate)diazepam (Valium)diuretics ('water pills') hormonal contraceptives (birth control pills, rings, patches, implants, injections, and intrauterine devices) indapamide (Natrilix) other medications for seizures such as carbamazepine (Carbatrol, Epitol, Equetro, Tegretol), phenobarbital, phenytoin (Dilantin), and valproic acid (Depakene, Depakote) proton-pump inhibitors such as lansoprazole (Prevacid), omeprazole (Prilosec), and pantoprazole (Protonix) theophylline (Theo-Dur) and selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), and sertraline (Zoloft).Other medications may interact with Trileptal, so be sure to tell your doctor and pharmacist about all the medications you are taking, even those that do not appear on this list. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- Tell your doctor if you have or have ever had kidney or liverdisease.
- Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you are using hormonal contraceptives , you should know that this type of birth control may not work well when taken with Trileptal. Hormonal contraceptives should not be prescribed as your only method of birth control while you are taking this medication. Talk to your doctor about birth control methods that will work for you. Call your doctor if you miss a period or think you may be pregnant while you are taking Trileptal.
- You should know that this medication may make you drowsy or dizzy, or may cause vision changes. Do not drive a car or operate machinery until you know how this medication affects you.

Interactions

Do not take Trileptal with any of the following drugs:
- Carbamazepine;
- Birth control pills;
- Chlorpropamide;
- Cyclophosphamide;
- Diuretics;
- Octreotide;
- Other drugs for seizures like phenobarbital, phenytoin, valproic acid;
- Some drugs for high blood pressure like felodipine, diltiazem, verapamil;
- Vincristine;

Side Effects

Trileptal side effects that you should report to your health care professional or doctor as soon as possible:
- Allergic reactions such as skin rash or itching, hives, swelling of the lips, mouth, tongue, or throat;
- Changes in vision;
- Confusion;
- Difficulty passing urine or change in the amount of urine;
- Fever;
- Infection;
- Nausea, vomiting;
- Problems with balance, speaking, walking;
- Swelling of feet, hands;
- Unusual bleeding, bruising;
- Unusually weak or tired;
- Worsening of mood, thoughts or actions of suicide or dying;
- Yellowing of eyes, skin;
- Constipation or diarrhea;
- Headache;
- Loss of appetite;
- Nervous;
- Stomach upset;
- Tremors;
- Trouble sleeping;
- Dizziness;
- Drowsiness;
- Vision changes;
- Double vision;
- Fast repeating eye movements that you cannot control;
- Diarrhea;
- Constipation;
- Heartburn;
- Stomach pain;
- Loss of appetite;
- Changes in the way food tastes;
- Dry mouth;
- Weight gain;
- Shaking of a part of the body that you cannot control;
- Difficulty coordinating movements;
- Falling down;
- Slowed movements or thoughts;
- Speech problems;
- Forgetfulness;
- Difficulty concentrating;
- Nervousness;
- Mood swings;
- Back pain;
- Muscle weakness or sudden tightness;
- Acne;
- Toothache;
- Earache;
- Hot flushes;
- Increased sweating;
- Cold symptoms;
- Nosebleed;
- Swelling redness irritation burning or itching of the vagina;
- White vaginal discharge;
- Swelling of the face throat tongue lips eyes hands feet ankles or lower legs;
- Seizures that last longer or happen more often than in the past;
- Headache;
- Unusual thirst;
- Upset stomach;
- Vomiting;
- Weakness;
- Confusion;
- Decreased alertness;
- Rash;
- Bumps or blisters in the mouth on skin or genitals;
- Red or purple-colored blotches or dots on skin;
- Red irritated eyes;
- Itching;
- Fever;
- Swollen glands in the neck or under the arms;
- Yellowing of the skin or eyes;
- Unusual bruising or bleeding;
- Bleeding from the rectum or blood in stools;
- Sore throat cough chills and other signs of infection;
- Increased decreased or painful urination;
- Joint pain;
- Chest pain;

Dosage

ADULTS

Trileptal taken alone

The usual starting dose is 300 mg twice daily. Your doctor may gradually increase the dose to 600 mg twice daily. In people with kidney disorders, the starting dose is 150 mg twice daily.

When changing from another antiepileptic medication to Trileptal

The usual starting dose is 300 mg twice daily. Your doctor will gradually increase the dose over a period of 2 to 4 weeks, while reducing the other medication over a period of 3 to 6 weeks. The final dosage of Trileptal is typically 1,200 mg twice daily.

Trileptal combined with another antiepileptic medication

The usual starting dose is 300 mg twice daily. Your doctor may increase the dose to 600 mg twice daily.

CHILDREN 4 TO 16 YEARS OLD

For children the dosage of Trileptal is based on body weight.

Trileptal taken alone

Your child's doctor will gradually increase the dose every 3 days until the most effective dose is reached. The usual dose ranges from 300 to 1,050 mg taken twice daily.

When changing from another antiepileptic medication to Trileptal

Your child's doctor will gradually increase the dose of Trileptal while reducing the other medication over a period of 3 to 6 weeks. The doctor will increase the dose of Trileptal weekly until the most effective dose is reached. The usual dose ranges from 300 to 1,050 mg taken twice daily.

Trileptal combined with another antiepileptic medication

After a 2-week buildup, the dosage typically ranges from 450 to 900 mg taken twice daily.

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