It is effective when prescribed alone or with thiazide diuretics that help rid the body of excess water.
It works by preventing the transformation of a hormone in your blood called angiotensin I into a more potent substance that increases salt and water retention in your body.
Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Univasc and you must continue taking it even if you are feeling well.
Univasc belongs to a family of drugs called angiotensin-converting enzyme (ACE) inhibitors.
Univasc does not cure high blood pressure it merely keeps it under control.
Univasc enhances blood flow throughout your blood vessels.
Univasc is prescribed in the treatment of high blood pressure.
You must take Univasc regularly for it to be effective.
Univasc side effects that you should report to your health care professional or doctor as soon as possible:
More common side effects may include:
- Flu-like symptoms;
Less common side effects may include:
- Sore throat;
- Muscle pain;
Rare side effects may include:
- Throbbing heartbeat;
- Sensitivity to light;
- Ringing in ears;
- Reduced amount of urine;
- Rash or skin disease;
- Mood changes;
- Low blood pressure;
- Liver disease;
- Light-headedness on standing up;
- Kidney problems;
- Joint pain;
- Irregular heart rhythm;
- Heart attack;
- Fluid retention;
- Feeling of illness;
- Dry mouth;
- Difficulty sleeping;
- Difficult or labored breathing;
- Chest pain;
- Changes in taste;
- Changes in appetite and weight;
- Abdominal pain;
Univasc is contraindicated if you have any of the following conditions:
- If you actually faint;
- If you are taking high doses of diuretics;
- If you are using bee or wasp venom to prevent severe reactions to stings;
- If you develop a persistent, dry cough;
- If you develop a sore throat or fever;
- If you have congestive heart failure or other heart or circulatory disorders;
- If you have ever had an allergic reaction to univasc or other ace inhibitors such as capoten, vasotec, and zestril;
- If you have kidney disease, diabetes, or a collagen-vascular disease such as lupus erythematosus or scleroderma;
- If you notice a yellow coloring to your skin or the whites of your eyes;
Do not take Univasc with any of the following drugs:
- Potassium-sparing diuretics (aldactone, moduretic, maxzide);
- Potassium supplements (slow-k);
- Lithium (eskalith, lithobid);
- Diuretics (diuril, hydrodiuril, lasix);
The safety and effectiveness of Univasc have not been established in children.
For people not taking a diuretic drug, the usual starting dose is 7.5 milligrams taken once a day, an hour before a meal.
The maximum dose is 60 milligrams per day.
The dosage after that can range from 7.5 to 30 milligrams per day, taken in either a single dose or divided into 2 equal doses daily.
Your doctor will closely monitor the effect of this drug and adjust it according to your individual needs.
This reduces the possibility of fainting or light-headedness.
People already taking a diuretic should stop taking it, if possible, 2 to 3 days before starting Univasc.
If Univasc alone does not control your blood pressure, your doctor will have you start taking a diuretic again.
If the diuretic cannot be discontinued, the starting dosage of Univasc should be 3.75 milligrams.
For people with kidney problems, the usual starting dose is 3.75 milligrams a day your doctor may gradually raise the dose to a maximum of 15 milligrams a day.
Although there is no specific information available, a sudden drop in blood pressure would be the most likely symptom of Univasc overdose.