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Enalapril, the ACE inhibitor, works by preventing a chemical in your blood called angiotensin I from converting into a more potent form that increases salt and water retention in your body. Enalapril enhances blood flow throughout your blood vessels.
Hydrochlorothiazide, a diuretic, prompts your body to produce and eliminate more urine, which helps in lowering blood pressure.
It combines an ACE inhibitor with a thiazide diuretic.
Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Vaseretic and you must continue taking it even if you are feeling well.
Vaseretic does not cure high blood pressure it merely keeps it under control.
Vaseretic is prescribed in the treatment of high blood pressure.
You must take Vaseretic regularly for it to be effective.

Side Effects

Vaseretic side effects that you should report to your health care professional or doctor as soon as possible:

More common side effects may include:
- Weakness;
- Weak or irregular heartbeat;
- Tingling or pins and needles;
- Rash;
- Nausea;
- Muscle pain or cramps);
- Muscle cramps;
- Low potassium levels (leading to symptoms such as dry mouth;
- Impotence;
- Headache;
- Fatigue;
- Excessive thirst;
- Drop in blood pressure upon standing up;
- Dizziness;
- Diarrhea;
- Cough;

Less common or rare side effects may include:
- Urinary tract infection;
- Then blue);
- Tearing;
- Stroke;
- Sore throat;
- Sleepiness;
- Shortness of breath;
- Sensitivity to light;
- Runny nose;
- Ringing in ears;
- Restlessness;
- Raynaud's phenomenon (in which the fingers periodically turn pale;
- Rash;
- Rapid heartbeat;
- Prickling;
- Or burning;
- Nervousness;
- Muscle cramps;
- Low blood pressure;
- Loss of hair;
- Loss of coordination;
- Loss of appetite;
- Liver failure;
- Kidney failure;
- Joint pain;
- Itching;
- Inflammation of the pancreas;
- Inflammation of mouth and tongue;
- Indigestion;
- Inability to sleep;
- Hoarseness;
- Hives;
- Hepatitis;
- Heart attack;
- Gout;
- Gas;
- Flushing;
- Fluid in lungs;
- Fainting;
- Excessive sweating;
- Dry mouth;
- Dry eyes;
- Disturbances in heart rhythm;
- Depression;
- Decrease in sex drive;
- Constipation;
- Conjunctivitis;
- Confusion;
- Chest pain;
- Bronchitis;
- Blurred vision;
- Blood clots in lungs;
- Blisters;
- Black stools;
- Back pain;
- Arthritis;
- Allergic reactions;
- Abnormal skin sensations such as numbness;
- Abnormal dreams;
- Abdominal pain;


Vaseretic is contraindicated if you have any of the following conditions:
- If you are diabetic, blood sugar levels should be monitored;
- If you are sensitive to or have ever had an allergic reaction to enalapril, hydrochlorothiazide, or similar drugs;
- If you are sensitive to other sulfa drugs;
- If you are taking bee or wasp venom to prevent an allergic reaction to stings;
- If you are taking vaseretic, a complete assessment of your kidney function should be done;
- If you develop chest pain, a sore throat, or fever you should contact your doctor immediately;
- If you develop swelling of your face, eyes, lips, tongue, or throat; swelling of your arms and legs; or difficulty swallowing;
- If you have a history of angioedema (swelling of face, extremities, and throat) or inability to urinate;
- If you have liver disease or lupus erythematosus (a form of rheumatism), vaseretic should be prescribed with caution;
- If you have severe congestive heart failure, you should be carefully watched for low blood pressure;
- If your skin or the whites of your eyes turn yellow, stop taking vaseretic and notify your doctor at once;


Do not take Vaseretic with any of the following drugs:
- Potassium-sparing diuretics such as midamor;
- Potassium-containing salt substitutes;
- Potassium supplements (k-lyte, k-tab, others);
- Oral antidiabetic drugs such as micronase;
- Norepinephrine;
- Nonsteroidal anti-inflammatory drugs such as naprosyn, advil, and motrin;
- Narcotics (percocet);
- Lithium (eskalith, lithonate);
- Insulin;
- Digitalis (lanoxin);
- Corticosteroids such as prednisone;
- Certain other antihypertensives;
- Barbiturates such as phenobarbital;
- Alcohol;



The doctor will adjust your dosage until your blood pressure is in the desired range.
For the 10/25 combination, the maximum is 2 tablets.
If you are taking the 5 milligrams enalapril/12.5 milligrams hydrochlorothiazide combination, the maximum daily dosage is 4 tablets.


Your doctor will prescribe Vaseretic cautiously, starting with small doses.


The safety and effectiveness of Vaseretic in children have not been established.


Symptoms of a Vaseretic overdose may include:
- Low blood pressure;
- Dehydration;
(c) 2017