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Zoloft

No Prescription

Zoloft is prescribed to treat depression. Zoloft is prescribed to treat obsessive compulsive disorder, panic disorder, post-trauma stress, premenstrual dysphoric disorder (PMDD) or social anxiety. Zoloft is prescribed to treat:
- Social anxiety disorder;
- Posttraumatic stress disorder;
- Panic attacks;
- Obsessive-compulsive disorder;
- Depression;

Zoloft is prescribed to relieve the symptoms of premenstrual dysphoric disorder, including:
- Mood swings;
- Irritability;
- Breast tenderness;
- Bloating;

Zoloft works by increasing the amounts of serotonin, a natural substance in the brain that helps maintain mental balance.
Zoloft is in a class of antidepressants called selective serotonin reuptake inhibitors (SSRIs).

Contraindications

Zoloft is contraindicated if you have any of the following conditions:
- Bipolar disorder or a family history of bipolar disorder;
- Diabetes;
- Heart disease;
- Liver disease;
- Receiving electroconvulsive therapy;
- Seizures (convulsions);
- Suicidal thoughts, plans, or attempt by you or a family member;
- An unusual or allergic reaction to Zoloft, other drugs, foods, dyes, or preservatives;
- Pregnant or trying to get pregnant;
- Breast-feeding;
- Tell your doctor and pharmacist if you are allergic to Zoloft or any other medications. Before taking Zoloft liquid concentrate, tell your doctor if you are allergic to latex.
- Tell your doctor if you are taking monoamine oxidase (MAO) inhibitors, including isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate), or have stopped taking them within the past 2 weeks, or if you are taking pimozide (Orap). Your doctor will probably tell you not to take Zoloft. If you stop taking Zoloft, you should wait at least 2 weeks before you start to take an MAO inhibitor.
- Do not take disulfiram (Antabuse) while taking Zoloft concentrate.
- Tell your doctor and pharmacist what other script and nonscript medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin) antidepressants (mood elevators) such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil) aspirin and other nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn) cimetidine (Tagamet) diazepam (Valium) digoxin (Lanoxin) lithium (Eskalith, Lithobid) medications for anxiety, mental illness, Parkinson's disease, and seizures medications for irregular heartbeat such as flecainide (Tambocor) and propafenone (Rythmol) oral medications for diabetes such as tolbutamide (Orinase) medications for migraine headaches such as almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex), and zolmitriptan (Zomig) sedatives sibutramine (Meridia) sleeping pills and tranquilizers. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- Tell your doctor if you have recently had a heart attack and if you have or have ever had seizures or liver or heart disease.
- Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking Zoloft, call your doctor.
- You should know that Zoloft may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.

Interactions

Do not take Zoloft with any of the following drugs:
- Cisapride;
- Drugs called MAO Inhibitors like Nardil, Parnate, Marplan, Eldepryl;
- Pimozide;
- Procarbazine;
- St John's wort;
- Thioridazine;
- Amphetamine or dextroamphetamine;
- Aspirin and aspirin-like drugs;
- Certain diet drugs like dexfenfluramine, fenfluramine, phentermine, sibutramine;
- Certain migraine headache drugs like almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan;
- Linezolid;
- Drugs for sleep;
- Drugs that treat or prevent blood clots like warfarin, enoxaparin, and dalteparin;
- Drugs to control heart rhythm like flecainide or propafenone;
- Metoclopramide;
- NSAIDs, drugs for pain and inflammation, like ibuprofen or naproxen;
- Other drugs for depression, anxiety, or psychotic disturbances;
- Pentazocine;
- Ritonavir;
- Tolbutamide;
- Tramadol;

Side Effects

Zoloft side effects that you should report to your health care professional or doctor as soon as possible:
- Allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue;
- Black or bloody stools, blood in the urine or vomit;
- Fast, irregular heartbeat;
- Feeling faint or lightheaded, falls;
- Hallucination, loss of contact with reality;
- Seizures;
- Suicidal thoughts or other mood changes;
- Unusual bleeding or bruising;
- Unusually weak or tired;
- Vomiting;
- Change in appetite;
- Change in sex drive or performance;
- Diarrhea;
- Increased sweating;
- Indigestion, nausea;
- Tremors;
- Nausea;
- Diarrhea;
- Constipation;
- Vomiting;
- Dry mouth;
- Gas or bloating;
- Loss of appetite;
- Weight changes;
- Drowsiness;
- Dizziness;
- Excessive tiredness;
- Headache;
- Pain burning or tingling in the hands or feet;
- Nervousness;
- Uncontrollable shaking of a part of the body;
- Sore throat;
- Changes in sex drive or ability;

Overdose

Reported Zoloft overdose symptoms are:
- Hair loss;
- Changes in sex drive or ability;
- Drowsiness;
- Excessive tiredness;
- Difficulty falling asleep or staying asleep;
- Diarrhea;
- Vomiting;
- Rapid pounding or irregular heartbeat;
- Nausea;
- Dizziness;
- Excitement;
- Uncontrollable shaking of a part of the body;
- Seizures;
- Hallucinating (hearing voices or seeing things that do not exist);
- Unconsciousness;

Dosage

ADULTS

Depression or Obsessive Compulsive Disorder

The usual starting dose is 50 mg once a day, taken either in the morning or in the evening. The doctor may increase your dose depending upon your response. The maximum dose is 200 mg in a day.

Premenstrual Dysphoric Disorder

Doses may be prescribed throughout the menstrual cycle or limited to the 2 weeks preceding menstruation. The starting dose is 50 mg a day. If this proves insufficient, the doctor will increase the dose in 50-mg steps at the start of each new menstrual cycle up to a maximum of 100 mg per day in the 2-week regimen or 150 mg per day in the full-cycle regimen. (During the first 3 days of the 2-week regimen, doses are always limited to 50 mg.)

Panic Disorder, Post-traumatic Stress Disorder, and Social Anxiety Disorder

During the first week, the usual dose is 25 mg once a day. After that, the dose increases to 50 mg once a day. Depending on your response, you're the doctor may continue to increase your dose up to a maximum of 200 mg a day.

CHILDREN 6 TO 17 YEARS OLD

Obsessive-Compulsive Disorder

The starting dose for children aged 6 to 12 is 25 mg and for adolescents aged 13 to 17, 50 mg. The doctor will adjust the dose as necessary.

Safety and effectiveness have not been established for children under 6.

DOSAGE ADJUSTMENT

The doctor will need to reduce the dosage if you have liver disease.

(c) 2017