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Zyban

Structure

Each film coated tablet contains Bupropion hydrochloride 150 mg (As extended release tablets)

No Prescription

Zyban is prescribed for the treatment of depression.
It is prescribed as a smoking cessation treatment.

Dosage

For the treatment of major depression:

Adults: Initially, 150 mg once daily in the morning; titrate after no less than 4 days to 150 mg twice daily if needed.
The onset of antidepressant effects takes 1–3 weeks, maximal effect may not be noted for 4 weeks.
The lowest dosage that maintains remission is recommended.
Insomnia may be minimized by avoiding bedtime doses.

Elderly: See adult dosage; may require a reduced initial dose.
Adolescents and children: Safe and effective use has not been established.

For use as an adjunct in the management of smoking cessation in patients with nicotine withdrawal (dosages are lower than maximum dosages of bupropion for the treatment of major depression):
Adults: Initially, 150 mg once daily for the first 6 days, then 150 mg twice daily for the remainder of the treatment period; doses should be at least 8 hours apart.
Do not exceed 300 mg/day. Initiate bupropion therapy 1–2 weeks before the patient’s target smoking "quit day".
The goal is complete abstinence.
Bupropion should be continued for 7–12 weeks.

Elderly: See adult dosage; may require a reduced initial dose.
Adolescents and Children: Not recommended for smoking cessation.

Contraindications

Zyban SR is contraindicated in patients with seizure disorders.
Zyban SR is also contradicted in patients with a current or prior diagnosis of anorexia nervosa or bulimia nervosa because of a higher incidence of seizures in these patients.
Concurrent administration of bupropion HCl and a monoamine oxidase inhibitor is contraindicated.
At least 14 days should elapse between discontinuation of an MAO inhibitor and initiation of treatment with bupropion HCl.
Zyban SR is contraindicated in patients who have shown hypersensitivity to bupropion or the other ingredients that make up Zyban SR.

Package

- Blister pack of 10 tablets.
(c) 2017